SCHEMBL29469846

SCHEMBL29469846

Cc1ccc(S(N)(=O)=O)c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.62
CYP1A2 P05177 2/20 0.54
CA2 P00918 5/20 0.53
CA1 P00915 4/20 0.53
CA9 Q16790 3/20 0.53
CDK2 P24941 1/20 0.52
CA6 P23280 3/20 0.43
CA4 P22748 2/20 0.43
CYP2C9 P11712 2/20 0.43
CA12 O43570 2/20 0.43
CA5A P35218 2/20 0.43
CA7 P43166 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
CA14 Q9ULX7 1/20 0.43
GLO1 Q04760 2/20 0.43
FTO Q9C0B1 1/20 0.43
CYP2A6 P11509 1/20 0.42
MCL1 Q07820 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2649239 1.00 LDHA (0.62) LDHACYP1A2CA2CA1CA9
SCHEMBL13223071 0.88 CDK2 (0.62) LDHACYP1A2CA2CA1CA9
SCHEMBL15461564 0.81 CYP1A2 (0.56) LDHACYP1A2GLO1CYP2A6ALDH1A1
SCHEMBL640546 0.79 CYP1A2 (0.54) LDHACYP1A2CYP2A6HSD17B10ALDH1A1
SCHEMBL18889781 0.79 LDHA (0.62) LDHACA2CA1CA9CDK2
SCHEMBL11684694 0.79 CYP1A2 (0.54) LDHACYP1A2CYP2A6ALDH1A1
SCHEMBL2662857 0.79 CYP1A2 (0.54) LDHACYP1A2CYP2A6HSD17B10ALDH1A1
SCHEMBL11192937 0.78 CYP1A2 (0.52) LDHACYP1A2CYP2A6HSD17B10ALDH1A1
SCHEMBL30274447 0.78 CYP1A2 (0.52) LDHACYP1A2CYP2A6HSD17B10ALDH1A1
SCHEMBL9138970 0.77 CDK2 (0.78) LDHACA2CA1CA9CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
CN-119219809-A Fluorine-containing polymer, preparation method thereof and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
EP-4229048-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER The Broad Institute, Inc. (US) 2023-08-23 EP disclosed
WO-2022081807-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER THE BROAD INSTITUTE, INC. (US) 2022-04-21 WO disclosed