Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 5/20 | 0.53 |
| ▸ | SKP1 | P63208 | 5/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383762 | 1.00 | CKS1B (0.53) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL30708991 | 0.96 | KDM4E (0.50) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL30709009 | 0.87 | ADORA2A (0.46) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL30709007 | 0.87 | ADORA2A (0.46) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL31468250 | 0.86 | ADORA2A (0.53) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL4693817 | 0.83 | KDM4E (0.48) | CNR1KDM4ELMNAL3MBTL1GAA | |
| SCHEMBL23186821 | 0.82 | CKS1B (0.44) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL30709005 | 0.80 | CYP2A6 (0.42) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL5211789 | 0.79 | ADORA1 (0.42) | CNR1ADORA2ASMN1; SMN2ADORA1TP53 | |
| SCHEMBL4825069 | 0.79 | CNR1 (0.50) | CNR1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004812-A | Cis-4- (5, 6-diphenyl pyrazine-2-amino) cyclohexyloxy acetic acid compound, and preparation method and application thereof | 四川轻化工大学 | 2025-05-16 | — | — | CN | claimed |
| CN-115825304-B | Method for measuring related substances in selapage bulk drug by high performance liquid chromatography | 湖南方盛制药股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119504614-A | Cis-4- (5, 6-diphenyl pyrazine-2-amino) cyclohexyloxy acetic acid compound, and preparation method and application thereof | 四川轻化工大学 | 2025-02-25 | — | — | CN | claimed |
| CN-114213343-B | Preparation and purification methods of celecoxib intermediate | 江苏豪森药业集团有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117510465-A | 5, 6-diphenyl pyrazine-2-piperidine compound and preparation method and application thereof | 四川轻化工大学 | 2024-02-06 | — | — | CN | claimed |
| CN-117304174-A | 5, 6-diphenyl pyrazine-2-nitrogen heterocyclic compound and preparation method and application thereof | 四川轻化工大学 | 2023-12-29 | — | — | CN | claimed |
| CN-116947766-A | Preparation method of celecoxib intermediate | 普济生物科技（台州）有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-114213343-A | Preparation and purification method of celecoxib intermediate | 江苏豪森药业集团有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-120004812-A | Cis-4- (5, 6-diphenyl pyrazine-2-amino) cyclohexyloxy acetic acid compound, and preparation method and application thereof | 四川轻化工大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-119039207-B | Dibenzo [ c, g ] phenanthrene derivative and organic electroluminescent device thereof | 西安欧得光电材料有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-115825304-B | Method for measuring related substances in selapage bulk drug by high performance liquid chromatography | 湖南方盛制药股份有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119504614-A | Cis-4- (5, 6-diphenyl pyrazine-2-amino) cyclohexyloxy acetic acid compound, and preparation method and application thereof | 四川轻化工大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-119320360-A | In the selapage Process for the preparation of intermediates | 重庆圣华曦药业股份有限公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-119143682-A | Selapa (Seapa) lattice intermediates preparation method of selapage | 湖北生物医药产业技术研究院有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-115015457-A | Method for analyzing bromoacetic acid impurities in serapager by high performance liquid chromatography | 湖南方盛制药股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| CN-113214169-B | Synthetic method of celecoxib intermediate | 江苏海洋大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114213343-A | Preparation and purification method of celecoxib intermediate | 江苏豪森药业集团有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114213343-A | Preparation and purification method of celecoxib intermediate | 江苏豪森药业集团有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114163441-A | Organic compound, organic light emitting diode including the same, and organic light emitting device | 乐金显示有限公司 | 2022-03-11 | — | — | CN | disclosed |