Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25207949 | 0.89 | HPGD (0.43) | HPGDGLASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL28289079 | 0.88 | CYP1A2 (0.55) | HPGDGLASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10960820 | 0.83 | — | — | |
| SCHEMBL14642043 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AALDH1A1APEX1 | |
| SCHEMBL22187119 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AALDH1A1APEX1 | |
| SCHEMBL14980473 | 0.82 | ALDH1A1 (0.51) | HPGDGLACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL18810404 | 0.82 | HPGD (0.50) | HPGDGLASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL26700145 | 0.82 | HPGD (0.50) | HPGDGLASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL14559155 | 0.82 | HPGD (0.50) | HPGDGLASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL22109111 | 0.80 | HPGD (0.49) | HPGDGLASMN1; SMN2CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053000-A1 | CARBOCYCLIC AMIDE DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2022-03-17 | — | — | WO | disclosed |