SCHEMBL29470904

SCHEMBL29470904

CC(C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.46
▸ IL23R Q5VWK5 3/20 0.45
▸ RAMP3 O60896 5/20 0.40
▸ CALCR P30988 5/20 0.40
▸ RXFP1 Q9HBX9 2/20 0.39
▸ PTH1R Q03431 1/20 0.39
▸ ECE1 P42892 1/20 0.38
▸ GLP1R P43220 1/20 0.38
▸ MUS81 Q96NY9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374718 0.91 TFPI (0.44) TFPIIL23R
SCHEMBL4755266 0.90 PTGS1 (0.46) —
SCHEMBL30469038 0.87 TFPI (0.45) TFPIIL23RRAMP3CALCR
SCHEMBL31393356 0.87 OPRM1 (0.43) IL23R
SCHEMBL30974395 0.87 TFPI (0.52) TFPIRAMP3CALCRRXFP1ECE1
SCHEMBL30484832 0.87 FNTA (0.42) TFPI
SCHEMBL30297059 0.86 IL23R (0.42) TFPIIL23R
SCHEMBL30006401 0.86 OPRM1 (0.46) IL23R
SCHEMBL30753508 0.85 PTGS1 (0.43) IL23R
SCHEMBL30753507 0.85 PTGS1 (0.40) TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333091-A Method for preparing HGH (176-191) by continuous flow solid phase synthesis 江苏诺泰澳赛诺生物制药股份有限公司 2023-06-27 — — CN claimed
CN-114380902-B Preparation method of HGH (176-191) 江苏诺泰澳赛诺生物制药股份有限公司 2023-06-16 — — CN claimed
CN-114380902-A Preparation method of HGH (176- 江苏诺泰澳赛诺生物制药股份有限公司 2022-04-22 — — CN claimed
CN-116333091-A Method for preparing HGH (176-191) by continuous flow solid phase synthesis 江苏诺泰澳赛诺生物制药股份有限公司 2023-06-27 — — CN disclosed
CN-114380902-B Preparation method of HGH (176-191) 江苏诺泰澳赛诺生物制药股份有限公司 2023-06-16 — — CN disclosed
CN-114380902-A Preparation method of HGH (176- 江苏诺泰澳赛诺生物制药股份有限公司 2022-04-22 — — CN disclosed
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