Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29470977 | 1.00 | RORC (0.42) | RORCWNT3ARETADRB2ADRB1 | |
| SCHEMBL29470980 | 1.00 | RORC (0.42) | RORCWNT3ARETADRB2ADRB1 | |
| SCHEMBL29470978 | 1.00 | RORC (0.42) | RORCWNT3ARETADRB2ADRB1 | |
| SCHEMBL19205759 | 1.00 | RORC (0.42) | RORCWNT3ARETADRB2ADRB1 | |
| SCHEMBL19205716 | 1.00 | RORC (0.42) | RORCWNT3ARETADRB2ADRB1 | |
| SCHEMBL18448791 | 1.00 | RORC (0.42) | RORCWNT3ARETADRB2ADRB1 | |
| SCHEMBL26382805 | 0.90 | RORC (0.42) | RORCWNT3ARETADRB2ADRB1 | |
| SCHEMBL18449666 | 0.89 | RORC (0.44) | RORCWNT3ARETCYP2D6PSEN1 | |
| SCHEMBL21133947 | 0.88 | RORC (0.44) | RORCWNT3ARETCYP2D6PSEN1 | |
| SCHEMBL29471013 | 0.88 | RORC (0.46) | RORCWNT3ARETCYP2D6PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669733-A | Polymorphic forms of rorgamma inhibiting compounds and methods of making the same | 格兰马克专业公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116669733-A | Polymorphic forms of rorgamma inhibiting compounds and methods of making the same | 格兰马克专业公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116669733-A | Polymorphic forms of rorgamma inhibiting compounds and methods of making the same | 格兰马克专业公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4208449-A1 | POLYMORPHIC FORMS OF A RORGAMMA INHIBITING COMPOUND AND PROCESSES FOR ITS PREPARATION | Glenmark Specialty S.A. (CH) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022049534-A1 | POLYMORPHIC FORMS OF A RORΓ INHIBITING COMPOUND AND PROCESSES FOR ITS PREPARATION | GLENMARK SPECIALTY S.A. (CH) | 2022-03-10 | — | — | WO | disclosed |