Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.47 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462660 | 0.93 | CASP3 (0.50) | CASP3MDM4TP53MDM2BACE1 | |
| SCHEMBL31210305 | 0.92 | MDM4 (0.51) | CASP3MDM4TP53MDM2TNF | |
| SCHEMBL22264471 | 0.88 | MDM4 (0.51) | CASP3MDM4TP53MDM2TNF | |
| SCHEMBL29372063 | 0.88 | MDM4 (0.51) | CASP3MDM4TP53MDM2TNF | |
| SCHEMBL29471032 | 0.88 | MDM4 (0.44) | CASP3MDM4TP53MDM2BACE1 | |
| SCHEMBL30107564 | 0.87 | CASP3 (0.54) | CASP3MDM4TP53MDM2BACE1 | |
| SCHEMBL30414754 | 0.84 | MDM2 (0.53) | CASP3MDM4TP53MDM2TNF | |
| SCHEMBL872021 | 0.84 | MDM4 (0.55) | CASP3MDM4TP53MDM2TNF | |
| SCHEMBL46349 | 0.84 | MDM4 (0.55) | CASP3MDM4TP53MDM2TNF | |
| SCHEMBL3722284 | 0.84 | MDM4 (0.55) | CASP3MDM4TP53MDM2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357314-A1 | METHODS FOR ULTRAFAST FORMATION OF DISULFIDE BONDS IN PEPTIDES AND PROTEINS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2023-11-09 | — | — | US | disclosed |
| WO-2022064500-A1 | METHODS FOR ULTRAFAST FORMATION OF DISULFIDE BONDS IN PEPTIDES AND PROTEINS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2022-03-31 | — | — | WO | disclosed |