Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 16/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | GPR4 | P46093 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26548437 | 1.00 | RET (0.42) | RETSQORNSD2GPR4LRRK2 | |
| SCHEMBL29471212 | 0.92 | GRM4 (0.38) | RET | |
| SCHEMBL29029078 | 0.92 | RET (0.35) | RET | |
| SCHEMBL24316690 | 0.92 | GRM4 (0.38) | RET | |
| SCHEMBL26112024 | 0.90 | CREBBP (0.36) | RETSQOR | |
| SCHEMBL24316581 | 0.88 | RET (0.36) | RET | |
| SCHEMBL29471251 | 0.88 | RET (0.36) | RET | |
| SCHEMBL31496193 | 0.87 | RET (0.42) | RET | |
| SCHEMBL24316580 | 0.87 | RET (0.37) | RET | |
| SCHEMBL29471231 | 0.86 | CREBBP (0.37) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4210683-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | Aurigene Oncology Limited (IN) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022053967-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2022-03-17 | — | — | WO | disclosed |