Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13715333 | 1.00 | KMT2A (0.46) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4568351 | 0.86 | KMT2A (0.47) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14174030 | 0.84 | KMT2A (0.46) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13715334 | 0.84 | LOXL2 (0.62) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1556278 | 0.84 | SMN1; SMN2 (0.47) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3276164 | 0.83 | KMT2A (0.51) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29866166 | 0.83 | KMT2A (0.51) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3697259 | 0.83 | CYP4F2 (0.48) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6489036 | 0.83 | KMT2A (0.53) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15281239 | 0.83 | KMT2A (0.50) | KMT2AMEN1L3MBTL1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114173772-A | Inhibitors of CD40-CD154 binding | 托尼克斯医药控股公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3952853-A1 | INHIBITORS OF CD40-CD154 BINDING | Tonix Pharmaceuticals Holding Corp. (US) | 2022-02-16 | — | — | EP | disclosed |