SCHEMBL29473430

CC(C)C[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	6/20	0.55

▸	GRPR	P30550	6/20	0.53

▸	OPRM1	P35372	2/20	0.49

▸	OPRD1	P41143	2/20	0.49

▸	GLP1R	P43220	3/20	0.47

▸	NPBWR1	P48145	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31494985	0.95	REN (0.53)	RENGRPROPRM1OPRD1GLP1R
SCHEMBL29473455	0.95	GRPR (0.57)	RENGRPROPRM1OPRD1NPBWR1
SCHEMBL38660507	0.94	GRPR (0.58)	GRPROPRM1OPRD1GLP1RNPBWR1
SCHEMBL30816315	0.92	GRPR (0.63)	RENGRPRGLP1R
SCHEMBL31223150	0.90	GRPR (0.61)	GRPROPRM1OPRD1GLP1R
SCHEMBL16716014	0.90	GRPR (0.57)	RENGRPR
SCHEMBL20764506	0.90	GRPR (0.59)	GRPROPRM1OPRD1GLP1R
SCHEMBL30398505	0.89	GRPR (0.64)	GRPR
SCHEMBL12767725	0.89	GRPR (0.58)	RENGRPRNPBWR1
SCHEMBL30118088	0.89	GRPR (0.62)	RENGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4188457-A1	CONJUGATE OR ITS SALT COMPRISING A GASTRIN-RELEASING PEPTIDE RECEPTOR ANTAGONIST AND USES THEREOF	Orano Med (FR)	2023-06-07	—	—	EP	claimed
WO-2022063850-A1	CONJUGATE OR ITS SALT COMPRISING A GASTRIN-RELEASING PEPTIDE RECEPTOR ANTAGONIST AND USES THEREOF	ORANO MED (FR)	2022-03-31	—	—	WO	claimed