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Sugi Predict / Compounds / SCHEMBL29473452

SCHEMBL29473452

SCHEMBL29473452

C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 4/20 0.59
▸ IL23R Q5VWK5 15/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30276229 0.97 IL23R (0.61) KISS1RIL23R
SCHEMBL30276262 0.97 IL23R (0.63) IL23R
SCHEMBL30276227 0.97 IL23R (0.63) IL23R
SCHEMBL29659636 0.97 IL23R (0.63) IL23R
SCHEMBL30276212 0.97 KISS1R (0.62) KISS1RIL23R
SCHEMBL30276256 0.95 IL23R (0.60) IL23R
SCHEMBL30276247 0.94 IL23R (0.61) IL23R
SCHEMBL29473462 0.94 IL23R (0.67) IL23R
SCHEMBL30276243 0.94 MC4R (0.53) KISS1RIL23R
SCHEMBL29659604 0.93 IL23R (0.59) IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3166967-B1 SYNTHETIC SOMATOSTATIN RECEPTOR LIGANDS TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD (IL) 2023-03-08 — — EP claimed
US-11827687-B2 Synthetic somatostatin receptor ligands TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) 2023-11-28 — — US disclosed
EP-3166967-B1 SYNTHETIC SOMATOSTATIN RECEPTOR LIGANDS TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD (IL) 2023-03-08 — — EP disclosed
US-20220162284-A1 SYNTHETIC SOMATOSTATIN RECEPTOR LIGANDS TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) 2022-05-26 — — US disclosed
US-11261230-B2 Synthetic somatostatin receptor ligands RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2022-03-01 — — US disclosed
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