Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.71 |
| ▸ | RXRB | P28702 | 11/20 | 0.71 |
| ▸ | RXRG | P48443 | 6/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035502 | 0.84 | RXRA (1.00) | RXRARXRBRXRGCA1CA2 | |
| SCHEMBL23698041 | 0.84 | RXRA (1.00) | RXRARXRBRXRGSRD5A2MAP4K4 | |
| SCHEMBL31133384 | 0.81 | RXRA (0.51) | RXRARXRBRXRGCA1CA2 | |
| SCHEMBL627645 | 0.81 | RXRA (0.51) | RXRARXRBRXRGCA1CA2 | |
| SCHEMBL4145328 | 0.80 | RXRA (0.78) | RXRARXRBRXRGCA1CA2 | |
| SCHEMBL29473789 | 0.78 | RXRA (0.81) | RXRARXRBRXRGCA1CA2 | |
| SCHEMBL18001609 | 0.78 | RXRA (0.59) | RXRARXRBRXRG | |
| SCHEMBL23910108 | 0.78 | RXRA (0.59) | RXRARXRBRXRG | |
| SCHEMBL6733430 | 0.76 | ABL1 (0.57) | RXRARXRBRXRG | |
| SCHEMBL13247923 | 0.76 | RXRA (0.55) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045494-B | Pyridone derivative and application thereof in preparation of drugs for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis | 四川大学华西医院 | 2022-04-26 | — | — | CN | disclosed |