Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29474915 | 1.00 | PPARD (0.54) | PPARDPPARAHDAC1HDAC2HDAC8 | |
| SCHEMBL29474935 | 0.99 | PPARD (0.54) | PPARDPPARAHDAC1HDAC2HDAC8 | |
| SCHEMBL29474914 | 0.97 | PPARD (0.56) | PPARDPPARAHDAC1HDAC2HDAC8 | |
| SCHEMBL29474932 | 0.97 | PPARD (0.53) | PPARDPPARAHDAC1HDAC2HDAC8 | |
| SCHEMBL29474934 | 0.90 | CA9 (0.56) | CA9DRD2RAB9AMEN1KMT2A | |
| SCHEMBL29474916 | 0.90 | CA9 (0.56) | CA9DRD2RAB9AMEN1KMT2A | |
| SCHEMBL29474937 | 0.89 | RAB9A (0.57) | CA9DRD2RAB9AMEN1KMT2A | |
| SCHEMBL29474925 | 0.88 | HDAC1 (0.56) | PPARDPPARAHDAC1HDAC2HDAC8 | |
| SCHEMBL29474930 | 0.88 | HDAC1 (0.56) | PPARDPPARAHDAC1HDAC2HDAC8 | |
| SCHEMBL29474913 | 0.88 | CA9 (0.55) | CA9DRD2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897031-B | Benzothiazole derivative containing coumarin group and preparation method and application thereof | 南京农业大学 | 2022-03-15 | — | — | CN | claimed |