Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | LGMN | Q99538 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.32 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.32 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82051 | 1.00 | RPS6KA3 (0.35) | RPS6KA3RPS6KA2RPS6KA1FYNPRKDC | |
| SCHEMBL82052 | 1.00 | RPS6KA3 (0.35) | RPS6KA3RPS6KA2RPS6KA1FYNPRKDC | |
| SCHEMBL86669 | 0.87 | PLOD2 (0.43) | RPS6KA3RPS6KA2RPS6KA1PRKDCPIK3CD | |
| SCHEMBL87428 | 0.81 | SMN1; SMN2 (0.42) | PLOD2PLOD3PLOD1MAPTSMN1; SMN2 | |
| SCHEMBL29475048 | 0.78 | PIK3CA (0.37) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL82608 | 0.78 | PIK3CA (0.37) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL82609 | 0.78 | PIK3CA (0.37) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL81686 | 0.78 | MTOR (0.37) | PIK3CAMAPTSMN1; SMN2RAB9AHPGD | |
| SCHEMBL81685 | 0.78 | MTOR (0.37) | PIK3CAMAPTSMN1; SMN2RAB9AHPGD | |
| SCHEMBL14041032 | 0.77 | PLOD2 (0.43) | RPS6KA3RPS6KA2RPS6KA1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109729716-B | PI3K inhibitor combination | 拜耳制药股份公司 | 2022-03-15 | — | — | CN | disclosed |