Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.62 |
| ▸ | IL6 | P05231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22359255 | 1.00 | TLR7 (0.62) | TLR7IL6 | |
| SCHEMBL26347149 | 0.91 | TLR7 (0.59) | TLR7IL6 | |
| SCHEMBL26347148 | 0.87 | TLR7 (0.70) | TLR7 | |
| SCHEMBL1145701 | 0.83 | TLR7 (0.79) | TLR7 | |
| SCHEMBL29475696 | 0.81 | TLR7 (0.74) | TLR7 | |
| SCHEMBL22359254 | 0.81 | TLR7 (0.74) | TLR7 | |
| SCHEMBL26347160 | 0.78 | TLR7 (0.84) | TLR7IL6 | |
| SCHEMBL22359348 | 0.77 | TLR7 (0.82) | TLR7IL6 | |
| SCHEMBL17417198 | 0.77 | TLR7 (1.00) | TLR7 | |
| SCHEMBL29391106 | 0.77 | TLR7 (1.00) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4199968-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | Ambrx, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040596-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | AMBRX, INC. (US) | 2022-02-24 | — | — | WO | disclosed |