SCHEMBL29475696

SCHEMBL29475696

CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(CCNC(=O)CON)CC4)nc3)c2n1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22359254 1.00 TLR7 (0.74) TLR7
SCHEMBL26347138 0.87 TLR7 (0.85) TLR7
SCHEMBL1146365 0.85 TLR7 (1.00) TLR7
SCHEMBL1146587 0.83 TLR7 (0.94) TLR7
SCHEMBL1146337 0.82 TLR7 (1.00) TLR7
SCHEMBL29475683 0.81 TLR7 (0.62) TLR7
SCHEMBL22359255 0.81 TLR7 (0.62) TLR7
SCHEMBL1145776 0.80 TLR7 (1.00) TLR7
SCHEMBL1145852 0.78 TLR7 (1.00) TLR7
SCHEMBL12867913 0.78 TLR7 (1.00) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4199968-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF Ambrx, Inc. (US) 2023-06-28 — — EP disclosed
WO-2022040596-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2022-02-24 — — WO disclosed
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