Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.55 |
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSH | P09668 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.54 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29476509 | 1.00 | KISS1R (0.55) | KISS1RDPP3CTSLCTSSCTSK | |
| SCHEMBL29476408 | 0.96 | KISS1R (0.53) | KISS1RDPP3CTSLCTSSCTSK | |
| SCHEMBL31620052 | 0.94 | C5AR1 (0.57) | KISS1RDPP3CXCR4C5AR1IL23R | |
| SCHEMBL29476485 | 0.92 | DPP3 (0.55) | KISS1RDPP3CXCR4C5AR1IL23R | |
| SCHEMBL29476615 | 0.92 | DPP3 (0.55) | KISS1RDPP3CXCR4C5AR1IL23R | |
| SCHEMBL30264942 | 0.91 | KISS1R (0.52) | KISS1RDPP3CTSLCTSSCTSK | |
| SCHEMBL30264798 | 0.91 | KISS1R (0.52) | KISS1RDPP3CTSLCTSSCTSK | |
| SCHEMBL31376716 | 0.90 | CXCR4 (0.55) | KISS1RDPP3CTSLCTSSCTSK | |
| SCHEMBL31665911 | 0.90 | CXCR4 (0.61) | KISS1RCXCR4C5AR1IL23RNTSR2 | |
| SCHEMBL29546449 | 0.90 | C5AR1 (0.56) | KISS1RDPP3CXCR4C5AR1IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271400-A | Peptide composition | 节奏制药公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118240012-A | Peptide composition | 节奏制药公司 | 2024-06-25 | — | — | CN | claimed |
| CN-105492456-B | Peptide composition | 节奏制药公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118271400-A | Peptide composition | 节奏制药公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118240012-A | Peptide composition | 节奏制药公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-4216979-A1 | METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS | Rhythm Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116507353-A | Methods of treating melanocortin-4 receptor pathway-related disorders | 节奏制药公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-115957297-A | Pharmaceutical composition | 节奏制药公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115957296-A | Pharmaceutical composition | 节奏制药公司 | 2023-04-14 | — | — | CN | disclosed |
| WO-2022067086-A1 | METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS | RHYTHM PHARMACEUTICALS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |