SCHEMBL2947656

SCHEMBL2947656

C=CSC=C.Cc1cc(CCC(=O)O)cc(C(C)(C)C)c1O.Cc1cc(CCC(=O)O)cc(C(C)(C)C)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.46
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.42
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
AGTR1 P30556 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
VCAM1 P19320 2/20 0.38
USP2 O75604 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489832 1.00 GAA (0.46) GAAKMT2AMEN1CYP1A2CYP2C9
SCHEMBL31230461 0.92 GAA (0.54) GAAKMT2AMEN1CYP1A2ALDH1A1
SCHEMBL431482 0.92 GAA (0.54) GAAKMT2AMEN1CYP1A2ALDH1A1
Ethylene SCHEMBL4043660 0.89 GAA (0.52) GAAKMT2AMEN1CYP1A2CYP2C9
Ethylene SCHEMBL21753792 0.89 GAA (0.52) GAAKMT2AMEN1CYP1A2CYP2C9
Ethylene SCHEMBL27695680 0.89 GAA (0.52) GAAKMT2AMEN1CYP1A2CYP2C9
SCHEMBL29387462 0.89 GAA (0.55) GAAKMT2AMEN1CYP1A2CYP2C9
Hydrogen Peroxide SCHEMBL28104512 0.89 GAA (0.55) GAAKMT2AMEN1CYP1A2CYP2C9
SCHEMBL39866 0.89 GAA (0.55) GAAKMT2AMEN1CYP1A2CYP2C9
Ammonia Solution, Strong SCHEMBL5491694 0.88 GAA (0.54) GAAKMT2AMEN1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137540-B1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION CYTEC IND INC (US) 2024-10-30 EP claimed
EP-2864310-B1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECH CORP (US) 2022-10-26 EP claimed
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. 2022-07-07 US claimed
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM CYTEC TECHNOLOGY CORP. 2022-05-19 US claimed
US-10975278-B2 Granular stabilizer compositions for use in polymer resins and methods of making same CYTEC INDUSTRIES INC. (US) 2021-04-13 US claimed
EP-2652014-B1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECH CORP (US) 2020-07-01 EP claimed
US-10407563-B2 Processes for producing molded articles stabilized against ultraviolet light and thermal degradation CYTEC INDUSTRIES INC. (US) 2019-09-10 US claimed
US-20190264084-A1 GRANULAR STABILIZER COMPOSITIONS FOR USE IN POLYMER RESINS AND METHODS OF MAKING SAME CYTEC INDUSTRIES INC. (US) 2019-08-29 US claimed
US-20170349730-A1 PROCESSES FOR PRODUCING MOLDED ARTICLES STABILIZED AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2017-12-07 US claimed
US-9725579-B2 Stabilizing compositions for stabilizing materials against ultraviolet light and thermal degradation CYTEC INDUSTRIES INC. (US) 2017-08-08 US claimed
US-20150315465-A1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2015-11-05 US claimed
US-8501846-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2013-08-06 US claimed
US-20130145962-A1 Stabilizer Compositions Containing Substituted Chroman Compounds and Methods of Use CYTEC TECHNOLOGY CORP. (US) 2013-06-13 US claimed
US-20120146257-A1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. (US) 2012-06-14 US claimed
US-20100256266-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2010-10-07 US claimed
US-7759417-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2010-07-20 US claimed
US-20090149581-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2009-06-11 US claimed
EP-3786216-B1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECH CORP (US) 2026-02-11 EP disclosed
WO-2007149082-A1 THERMOPLASTIC RESIN COMPOSITIONS SUITABLE FOR USE IN TRANSPARENT LAMINATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-27 WO disclosed
US-20070289693-A1 Thermoplastic resin compositions suitable for use in transparent laminates E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220212375-A1 POLYMERIC HOLLOW ARTICLES CONTAINING CHROMAN-BASED COMPOUNDS AND MADE BY ROTATIONAL MOLDING RPS7, MRPS27, F7 GAA 1545/4885KMT2A 3197/4885MEN1 1598/4885
US-20220153959-A1 POLYOLEFIN COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND MOLDED ARTICLES PRODUCED THEREFROM NOTUM, PMM2, WASF2 GAA 905/4885KMT2A 1457/4885MEN1 620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.