Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 5/20 | 0.60 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | NPY1R | P25929 | 3/20 | 0.56 |
| ▸ | NPY2R | P49146 | 3/20 | 0.56 |
| ▸ | NPY4R | P50391 | 3/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.56 |
| ▸ | CCKAR | P32238 | 1/20 | 0.56 |
| ▸ | CCKBR | P32239 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29476441 | 0.97 | KISS1R (0.55) | KISS1RIL23ROPRD1OPRM1NPY1R | |
| SCHEMBL29476439 | 0.97 | KISS1R (0.55) | KISS1RIL23ROPRD1OPRM1NPY1R | |
| SCHEMBL30264831 | 0.96 | KISS1R (0.59) | KISS1RIL23ROPRD1OPRM1NPY1R | |
| SCHEMBL30264620 | 0.95 | KISS1R (0.54) | KISS1RIL23ROPRD1NPBWR1CCKAR | |
| SCHEMBL29476520 | 0.93 | IL23R (0.54) | KISS1RIL23R | |
| SCHEMBL29476435 | 0.93 | IL23R (0.54) | KISS1RIL23R | |
| SCHEMBL30264784 | 0.93 | KISS1R (0.55) | KISS1RIL23RNPY1RNPY2RNPY4R | |
| SCHEMBL30264819 | 0.93 | KISS1R (0.55) | KISS1RIL23RNPY1RNPY2RNPY4R | |
| SCHEMBL30264867 | 0.93 | KISS1R (0.55) | KISS1RIL23RNPY1RNPY2RNPY4R | |
| SCHEMBL29511018 | 0.93 | KISS1R (0.58) | KISS1RIL23ROPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492456-B | Peptide composition | 节奏制药公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118271400-A | Peptide composition | 节奏制药公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118240012-A | Peptide composition | 节奏制药公司 | 2024-06-25 | — | — | CN | claimed |
| CN-105492456-B | Peptide composition | 节奏制药公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118271400-A | Peptide composition | 节奏制药公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118240012-A | Peptide composition | 节奏制药公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-4216979-A1 | METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS | Rhythm Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116507353-A | Methods of treating melanocortin-4 receptor pathway-related disorders | 节奏制药公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-115957297-A | Pharmaceutical composition | 节奏制药公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115957296-A | Pharmaceutical composition | 节奏制药公司 | 2023-04-14 | — | — | CN | disclosed |
| WO-2022067086-A1 | METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS | RHYTHM PHARMACEUTICALS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |