SCHEMBL2947664

SCHEMBL2947664

Cc1cc(C)c(Oc2ccc(N)cc2)c(C(C)(C)c2cc(C)cc(C)c2Oc2ccc(N)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
TEAD4 Q15561 1/20 0.47
MAPT P10636 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
POLB P06746 1/20 0.46
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
MAPK1 P28482 2/20 0.43
HPGD P15428 1/20 0.43
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
AR P10275 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MITF O75030 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
NLRP1 Q9C000 1/20 0.38
NOD2 Q9HC29 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2940117 0.85 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9321941 0.84 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL10409619 0.83 MAPT (0.47) ALDH1A1SMN1; SMN2MAPTPOLBCYP3A4
SCHEMBL7610901 0.83 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL1854909 0.80 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL10816306 0.79 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL25920604 0.77 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9082044 0.77 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL26604996 0.77 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL26228778 0.76 TEAD4 (0.55) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7751020-B2 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. (JP) 2010-07-06 US disclosed
US-7643119-B2 Liquid crystal display device having improved spacers HITACHI, LTD. (JP) 2010-01-05 US disclosed
US-20090051864-A1 Liquid crystal display device having improved spacers HITACHI, LTD. 2009-02-26 US disclosed
US-20070040984-A1 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. 2007-02-22 US disclosed
US-7167228-B2 Liquid crystal display device with two kinds of projected portions on a substrate HITACHI, LTD. (JP) 2007-01-23 US disclosed
US-7050140-B2 Liquid crystal display device with spacers formed on a planarizing film disposed over color filters HITACHI, LTD. (JP) 2006-05-23 US disclosed
US-7012668-B2 Method of measuring AC residual image in a liquid crystal display device HITACHI, LTD. (JP) 2006-03-14 US disclosed
US-20050200795-A1 Liquid crystal display device IPS ALPHA SUPPORT CO., LTD. (JP) 2005-09-15 US disclosed
US-20040257483-A1 LIQUID CRYSTAL DISPLAY DEVICE WITH SPACERS FORMED ON A PLANARIZING FILM DISPOSED OVER COLOR FILTERS HITACHI, LTD. 2004-12-23 US disclosed
US-6798486-B2 Liquid crystal display device with spacers formed on a planarizing film disposed over color filters HITACHI, LTD. (JP) 2004-09-28 US disclosed
US-20030151716-A1 Liquid crystal display device HITACHI, LTD. 2003-08-14 US disclosed
US-6583846-B1 Liquid crystal display device with spacer covered with an electrode HITACHI, LTD. (JP) 2003-06-24 US disclosed
US-20030020864-A1 Liquid crystal display device HITACHI, LTD. 2003-01-30 US disclosed
EP-1156363-A1 LIQUID CRYSTAL DISPLAY ELEMENT Hitachi, Ltd. (JP) 2001-11-21 EP disclosed