Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 6/20 | 0.36 |
| ▸ | ACE | P12821 | 5/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL5519894 | 0.94 | SLC7A5 (0.49) | SLC7A5KISS1RANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL3442322 | 0.89 | SLC7A5 (0.55) | SLC7A5ACEANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL27814390 | 0.87 | SLC7A5 (0.57) | SLC7A5ACEMMECPA1ACE2 | |
| Tyrosine SCHEMBL9453454 | 0.87 | SLC7A5 (0.39) | SLC7A5ACEANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL20857031 | 0.85 | SLC7A5 (0.52) | SLC7A5ACEANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL3131438 | 0.84 | SLC7A5 (0.53) | SLC7A5ACEANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL3131428 | 0.84 | SLC7A5 (0.53) | SLC7A5ACEANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL27866450 | 0.84 | SLC7A5 (0.56) | SLC7A5ACEANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL28985775 | 0.84 | SLC7A5 (0.61) | SLC7A5 | |
| Tyrosine SCHEMBL18249988 | 0.84 | SLC7A5 (0.61) | SLC7A5ACEANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445325-B1 | PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF | HAYASHIBARA BIOCHEM LAB (JP) | 2010-05-26 | — | — | EP | claimed |
| EP-2463378-B1 | Alpha isomaltosylglucosaccharide synthase, process for producing the same and use thereof | HAYASHIBARA CO (JP) | 2015-12-23 | — | — | EP | disclosed |
| EP-2463378-A1 | Alpha isomaltosylglucosaccharide synthase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-06-13 | — | — | EP | disclosed |
| EP-1229112-B1 | ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | HAYASHIBARA BIOCHEM LAB (JP) | 2012-03-14 | — | — | EP | disclosed |
| US-7811797-B2 | α-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-10-12 | — | — | US | disclosed |
| EP-1445325-B1 | PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF | HAYASHIBARA BIOCHEM LAB (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-7718404-B2 | α-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-05-18 | — | — | US | disclosed |
| US-7592160-B2 | Processes for producing isomaltose and isomaltitol and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20080032350-A1 | Alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2008-02-07 | — | — | US | disclosed |
| US-20080003651-A1 | alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2008-01-03 | — | — | US | disclosed |
| US-7241606-B2 | α-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-07-10 | — | — | US | disclosed |
| US-7186701-B2 | Dehydrating agent and method for dehydrating moist article using the agent and dehydrated article obtained by the method | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-03-06 | — | — | US | disclosed |
| US-20060240531-A1 | Processes for producing isomaltose and isomaltitol and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2006-10-26 | — | — | US | disclosed |
| EP-1360988-B1 | METHOD FOR DEHYDRATING MOIST ARTICLE USING A CYCLOTETRASACCHARIDE | HAYASHIBARA BIOCHEM LAB (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-20060008791-A1 | Dehydrating agent and method for dehydrating moist article using the agent and dehydrated article obtained by the method | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2006-01-12 | — | — | US | disclosed |
| EP-1445325-A1 | PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-08-11 | — | — | EP | disclosed |
| EP-1360988-A1 | DEHYDRATING AGENT AND METHOD FOR DEHYDRATING MOIST ARTICLE USING THE AGENT AND DEHYDRATED ARTICLE OBTAINED BY THE METHOD | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-20030194762-A1 | Alpha-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2003-10-16 | — | — | US | disclosed |
| EP-1229112-A1 | ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2002-08-07 | — | — | EP | disclosed |