Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | NR1I3 | Q14994 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R)Pk-11195 SCHEMBL15118334 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| (R)Pk-11195 SCHEMBL7685386 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| Pk-11195 SCHEMBL117124 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| (R)Pk-11195 SCHEMBL29357086 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| (R)Pk-11195 SCHEMBL12790424 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| Pk-11195 SCHEMBL29354252 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| (R)Pk-11195 SCHEMBL3126094 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| Pk-11195 SCHEMBL31060347 | 1.00 | TSPO (1.00) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL3046732 | 0.89 | TSPO (0.81) | TSPOMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL3035734 | 0.89 | TSPO (0.81) | TSPOMEN1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250268847-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF DEMYELINATING DISORDERS | THE UNIVERSITY OF CHICAGO (US) | 2025-08-28 | — | — | US | disclosed |
| US-12310933-B2 | Treatment of demyelinating disorders | THE UNIVERSITY OF CHICAGO (US) | 2025-05-27 | — | — | US | disclosed |
| WO-2025068949-A1 | EMRUSOLMIN FOR USE IN TREATING MULTIPLE SYSTEM ATROPHY | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2025-04-03 | — | — | WO | disclosed |
| CN-118344351-A | Preparation method and application of PET imaging agent targeting neuroinflammatory purinergic P2Y12 receptor | 复旦大学 | 2024-07-16 | — | — | CN | disclosed |
| US-20240009332-A1 | COMPOSITE EMBOLIZATION BEADS | TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC | 2024-01-11 | — | — | US | disclosed |
| US-20230322897-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROCOGNITIVE DISORDERS | AVROBIO, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230243811-A1 | IDENTIFICATION OF TRANSPLANTED HUMAN CELLS | RIGSHOSPITALET (REGH) (DK) | 2023-08-03 | — | — | US | disclosed |
| US-11712487-B2 | Composite embolization beads | RAIKA MEDICAL IMAGING INC. (US) | 2023-08-01 | — | — | US | disclosed |
| US-11672468-B2 | System and method for multi-modality quantification of neuroinflammation in central nervous system diseases | WASHINGTON UNIVERSITY (US) | 2023-06-13 | — | — | US | disclosed |
| EP-4175717-A2 | COMPOSITIONS AND METHODS FOR TREATING NEUROCOGNITIVE DISORDERS | Avrobio, Inc. (US) | 2023-05-10 | — | — | EP | disclosed |
| US-20220133850-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROCOGNITIVE DISORDERS | AVROBIO, INC. | 2022-05-05 | — | — | US | disclosed |
| US-20220111005-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROCOGNITIVE DISORDERS | AVROBIO, INC. (US) | 2022-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250268847-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF DEMYELINATING DISORDERS | MAG, PMP22, GBA1 | TSPO 2564/4885MEN1 3520/4885KMT2A 2511/4885 |
| US-12310933-B2 | Treatment of demyelinating disorders | MAG, PMP22, GBA1 | TSPO 1892/4885MEN1 3454/4885KMT2A 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.