Piperettine

Piperettine

SCHEMBL29477286

O=C(CCCC/C=C/c1ccc2c(c1)OCO2)N1CCCCC1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 4/20 0.63
RAB9A P51151 3/20 0.60
NPC1 O15118 2/20 0.60
MAOB P27338 4/20 0.58
HPGD P15428 5/20 0.57
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
CYP3A4 P08684 3/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
HSD17B10 Q99714 2/20 0.57
HDAC6 Q9UBN7 2/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2D6 P10635 2/20 0.57
CTSD P07339 1/20 0.57
ABCB1 P08183 1/20 0.57
ALOX5 P09917 1/20 0.57
GABRA1 P14867 1/20 0.57
MAOA P21397 1/20 0.57
MAPK1 P28482 1/20 0.57
GABRB2 P47870 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperettine SCHEMBL15159493 1.00 TRPV1 (0.63) TRPV1RAB9ANPC1MAOBHPGD
Piperettine SCHEMBL29371038 1.00 TRPV1 (0.63) TRPV1RAB9ANPC1MAOBHPGD
SCHEMBL23728189 0.99 TRPV1 (0.61) TRPV1RAB9ANPC1MAOBHPGD
Piperrolein B SCHEMBL15471329 0.99 TRPV1 (0.61) TRPV1RAB9ANPC1MAOBHPGD
Piperrolein B SCHEMBL15159494 0.99 TRPV1 (0.61) TRPV1RAB9ANPC1MAOBHPGD
SCHEMBL3963336 0.98 TRPV1 (0.60) TRPV1RAB9ANPC1MAOBHPGD
SCHEMBL3963333 0.98 TRPV1 (0.60) TRPV1RAB9ANPC1MAOBHPGD
SCHEMBL14025734 0.98 TRPV1 (0.60) TRPV1RAB9ANPC1MAOBHPGD
SCHEMBL31329216 0.98 TRPV1 (0.60) TRPV1RAB9ANPC1MAOBHPGD
SCHEMBL24780959 0.92 TRPV1 (0.64) TRPV1RAB9ANPC1MAOBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4229639-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS Global Biopharma, Inc. (CA) 2023-08-23 EP claimed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 WO claimed
US-20250127805-A1 ALCOHOLIC FORMULATION WITH A MIXTURE OF ALKALOIDS, PRENOL LIPIDS AND FLAVONOIDS PONTIFICIA UNIVERSIDAD JAVERIANA (CO) 2025-04-24 US disclosed
CN-118948982-A Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis 尤尼根公司 2024-11-15 CN disclosed
CN-115515614-B Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis 尤尼根公司 2024-07-23 CN disclosed
CN-116270636-A Retina function injury protecting medicine 辛晓蓉 2023-06-23 CN disclosed
CN-115515614-A Compositions comprising extracts of alpinia and other plants for improving joint health and treating arthritis 尤尼根公司 2022-12-23 CN disclosed
EP-4100034-A1 COMPOSITIONS COMPRISING EXTRACTS OF APLINIA AND OTHER PLANTS FOR IMPROVING JOINT HEALTH AND TREATING ARTHRITIS Unigen, Inc. (US) 2022-12-14 EP disclosed
US-20220130493-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-28 US disclosed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 WO disclosed