Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963333 | 1.00 | TRPV1 (0.60) | TRPV1MAOBRAB9ANPC1HPGD | |
| SCHEMBL14025734 | 1.00 | TRPV1 (0.60) | TRPV1MAOBRAB9ANPC1HPGD | |
| SCHEMBL31329216 | 1.00 | TRPV1 (0.60) | TRPV1MAOBRAB9ANPC1HPGD | |
| SCHEMBL23728189 | 0.99 | TRPV1 (0.61) | TRPV1MAOBRAB9ANPC1HPGD | |
| Piperrolein B SCHEMBL15471329 | 0.99 | TRPV1 (0.61) | TRPV1MAOBRAB9ANPC1HPGD | |
| Piperrolein B SCHEMBL15159494 | 0.99 | TRPV1 (0.61) | TRPV1MAOBRAB9ANPC1HPGD | |
| Piperettine SCHEMBL15159493 | 0.98 | TRPV1 (0.63) | TRPV1MAOBRAB9ANPC1HPGD | |
| Piperettine SCHEMBL29477286 | 0.98 | TRPV1 (0.63) | TRPV1MAOBRAB9ANPC1HPGD | |
| Piperettine SCHEMBL29371038 | 0.98 | TRPV1 (0.63) | TRPV1MAOBRAB9ANPC1HPGD | |
| SCHEMBL24780959 | 0.90 | TRPV1 (0.64) | TRPV1MAOBRAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041786-A2 | PHARMACEUTICAL COMPOSITION COMPRISING INHIBITORS OF CELL ADHESION MOLECULE ISOLATED FROM PIPER LONGUM FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISEASE | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-04-02 | — | — | WO | disclosed |