Machilin G

Machilin G

SCHEMBL29477303

COc1ccc([C@@H]2O[C@@H](c3ccc4c(c3)OCO4)[C@H](C)[C@@H]2C)cc1OC

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 2/20 0.75
PTAFR P25105 1/20 0.72
SOAT1 P35610 8/20 0.70
HIF1A Q16665 2/20 0.69
EPAS1 Q99814 2/20 0.69
ACHE P22303 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Machilin G SCHEMBL31108393 1.00 MAPK9 (0.75) MAPK9PTAFRSOAT1HIF1AEPAS1
Machilin G SCHEMBL29477295 1.00 MAPK9 (0.75) MAPK9PTAFRSOAT1HIF1AEPAS1
SCHEMBL29477356 0.88 NR3C1 (0.74) MAPK9SOAT1HIF1AEPAS1
SCHEMBL12604782 0.88 NR3C1 (0.74) MAPK9SOAT1HIF1AEPAS1
SCHEMBL29477355 0.88 NR3C1 (0.74) MAPK9SOAT1HIF1AEPAS1
SCHEMBL12604779 0.88 NR3C1 (0.74) MAPK9SOAT1HIF1AEPAS1
SCHEMBL30678812 0.88 MAPK9 (0.69) MAPK9SOAT1HIF1AEPAS1
SCHEMBL30991863 0.88 NR3C1 (0.74) MAPK9SOAT1HIF1AEPAS1
SCHEMBL4737162 0.87 MAPK9 (1.00) MAPK9SOAT1HIF1AEPAS1
SCHEMBL29477291 0.87 MAPK9 (1.00) MAPK9SOAT1HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4229639-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS Global Biopharma, Inc. (CA) 2023-08-23 EP claimed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 WO claimed
US-20220130493-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-28 US disclosed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 WO disclosed