Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24365995 | 1.00 | PRMT5 (0.47) | PRMT5ESR2WDR77NR1H2NR1H3 | |
| SCHEMBL29081437 | 1.00 | PRMT5 (0.47) | PRMT5ESR2WDR77NR1H2NR1H3 | |
| SCHEMBL29477677 | 1.00 | PRMT5 (0.47) | PRMT5ESR2WDR77NR1H2NR1H3 | |
| SCHEMBL29081455 | 1.00 | PRMT5 (0.47) | PRMT5ESR2WDR77NR1H2NR1H3 | |
| SCHEMBL25326414 | 1.00 | PRMT5 (0.47) | PRMT5ESR2WDR77NR1H2NR1H3 | |
| SCHEMBL25323182 | 0.88 | NR1H2 (0.48) | PRMT5WDR77NR1H2NR1H3LMNA | |
| SCHEMBL25323185 | 0.88 | NR1H2 (0.48) | PRMT5WDR77NR1H2NR1H3LMNA | |
| SCHEMBL29324099 | 0.88 | NR1H2 (0.48) | PRMT5WDR77NR1H2NR1H3LMNA | |
| SCHEMBL29081369 | 0.88 | NR1H2 (0.48) | PRMT5WDR77NR1H2NR1H3LMNA | |
| SCHEMBL29081853 | 0.88 | NR1H2 (0.48) | PRMT5WDR77NR1H2NR1H3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-12304907-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-12264154-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-04-01 | — | — | US | disclosed |
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-08-22 | — | — | US | disclosed |
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20230113778-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-11492350-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | PRMT5 347/4885ESR2 935/4885WDR77 1263/4885 |
| US-11492350-B2 | Compounds and methods of use | F12, C1R, ABCG2 | PRMT5 347/4885ESR2 935/4885WDR77 1263/4885 |
| US-20230113778-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | PRMT5 347/4885ESR2 935/4885WDR77 1263/4885 |
| US-12264154-B2 | Compounds and methods of use | F12, C1R, ABCG2 | PRMT5 347/4885ESR2 935/4885WDR77 1263/4885 |
| US-12304907-B2 | Compounds and methods of use | F12, C1R, ABCG2 | PRMT5 347/4885ESR2 935/4885WDR77 1263/4885 |
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | PRMT5 347/4885ESR2 935/4885WDR77 1263/4885 |
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | PRMT5 347/4885ESR2 935/4885WDR77 1263/4885 |
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | NR3C2, ADRA1A, CNR1 | PRMT5 3142/4885ESR2 182/4885WDR77 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.