SCHEMBL29478041

SCHEMBL29478041

CC(=O)N(Cc1ccccc1OCCF)c1cnccc1Oc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSPO P30536 7/20 0.86
ALB P02768 1/20 0.86
OPRK1 P41145 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2757554 1.00 TSPO (0.86) TSPOALBOPRK1
SCHEMBL16569003 0.93 TSPO (1.00) TSPOALBOPRK1
SCHEMBL12405739 0.91 TSPO (0.78) TSPOALBOPRK1
SCHEMBL18068951 0.90 TSPO (0.83) TSPOALBOPRK1
SCHEMBL2757580 0.89 TSPO (0.69) TSPOALBOPRK1
SCHEMBL2757551 0.87 TSPO (1.00) TSPOALBOPRK1
SCHEMBL2757548 0.87 TSPO (1.00) TSPOALBOPRK1
SCHEMBL29377466 0.87 TSPO (1.00) TSPOALBOPRK1
SCHEMBL2757561 0.86 TSPO (0.65) TSPOALBOPRK1
SCHEMBL13161736 0.86 TSPO (0.65) TSPOALBOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129065-B1 TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS AKAMARA THERAPEUTICS INC (US) 2026-05-13 EP disclosed
US-20250195602-A1 Compositions and Methods for Treating Neuropathy CREATIVE BIO-PEPTIDES, INC. 2025-06-19 US disclosed
US-12325744-B2 Methods for reducing post-operative cognitive dysfunction (POCD) THE KENNEDY TRUST FOR RHEUMATOLOGY RESEARCH (GB) 2025-06-10 US disclosed
WO-2025038692-A2 DEEP REGRESSION ESTIMATION OF ARTERIAL INPUT FUNCTION FOR DYNAMIC PET THE JOHNS HOPKINS UNIVERSITY (US) 2025-02-20 WO disclosed
US-20240252583-A1 Compositions and Methods for Treating Persistent Postsurgical Pain CREATIVE BIO-PEPTIDES, INC. 2024-08-01 US disclosed
US-20240197700-A1 Methods and Compositions for Treating Lysosomal Storage Disorders HEALTH, SANFORD 2024-06-20 US disclosed
EP-4352075-A1 COMPOSITIONS AND METHODS FOR TREATING PERSISTENT POSTSURGICAL PAIN Creative Bio-Peptides Inc. (US) 2024-04-17 EP disclosed
EP-4340860-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY Creative Bio-Peptides Inc. (US) 2024-03-27 EP disclosed
EP-4313016-A1 METHODS AND COMPOSITIONS FOR TREATING LYSOSOMAL STORAGE DISORDERS Sanford Health (US) 2024-02-07 EP disclosed
US-20240009332-A1 COMPOSITE EMBOLIZATION BEADS TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC 2024-01-11 US disclosed
US-11712487-B2 Composite embolization beads RAIKA MEDICAL IMAGING INC. (US) 2023-08-01 US disclosed
US-11701429-B2 Targeted drug delivery through affinity based linkers Akamara Therapeutics, Inc. (US) 2023-07-18 US disclosed
CN-113387896-B 4- (2-chloro aryl) quinazoline-2-amide derivative and application thereof 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) 2023-03-24 CN disclosed
WO-2022261321-A1 COMPOSITIONS AND METHODS FOR TREATING PERSISTENT POSTSURGICAL PAIN CREATIVE BIO-PEPTIDES, INC. (US) 2022-12-15 WO disclosed
CN-110229093-B Carbazole compounds for in vivo imaging 通用电气健康护理有限公司 2022-12-13 CN disclosed
WO-2022246233-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY CREATIVE BIO-PEPTIDES, INC. (US) 2022-11-24 WO disclosed
WO-2022212273-A1 METHODS AND COMPOSITIONS FOR TREATING LYSOSOMAL STORAGE DISORDERS SANFORD HEALTH (US) 2022-10-06 WO disclosed
WO-2022212271-A1 METHODS AND COMPOSITIONS FOR TREATING LYSOSOMAL STORAGE DISORDERS SANFORD HEALTH (US) 2022-10-06 WO disclosed
WO-2022212268-A1 METHODS AND COMPOSITIONS FOR TREATING LYSOSOMAL STORAGE DISORDERS SANFORD HEALTH (US) 2022-10-06 WO disclosed
US-20220112281-A1 METHODS FOR REDUCING POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) THE KENNEDY TRUST FOR RHEUMATOLOGY RESEARCH (GB) 2022-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701429-B2 Targeted drug delivery through affinity based linkers ABCG2, FCGR2A, ABCB1 TSPO 264/4885ALB 142/4885OPRK1 2863/4885
US-20240197700-A1 Methods and Compositions for Treating Lysosomal Storage Disorders GAA, GBA1, MAN2B1 TSPO 1844/4885ALB 2713/4885OPRK1 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.