SCHEMBL29478366

SCHEMBL29478366

N[C@H](CC(=O)O)Cc1ccccc1C(F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.58
DPP7 Q9UHL4 1/20 0.58
PPARG P37231 3/20 0.48
PPARA Q07869 1/20 0.48
POLQ O75417 1/20 0.44
DPP8 Q6V1X1 3/20 0.44
FAP Q12884 2/20 0.44
DPP9 Q86TI2 2/20 0.44
IDO1 P14902 2/20 0.44
MAOB P27338 1/20 0.43
POLB P06746 1/20 0.42
EPHX2 P34913 4/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29478373 1.00 DPP4 (0.58) DPP4DPP7PPARGPPARAPOLQ
SCHEMBL975350 1.00 DPP4 (0.58) DPP4DPP7PPARGPPARAPOLQ
SCHEMBL975351 1.00 DPP4 (0.58) DPP4DPP7PPARGPPARAPOLQ
SCHEMBL2028473 1.00 DPP4 (0.58) DPP4DPP7PPARGPPARAPOLQ
Hydrochloric Acid SCHEMBL14118972 0.98 DPP4 (0.57) DPP4DPP7PPARGPPARAPOLQ
Hydrochloric Acid SCHEMBL1311085 0.98 DPP4 (0.57) DPP4DPP7PPARGPPARAPOLQ
SCHEMBL20038786 0.88 DPP4 (0.47) DPP4DPP7PPARGPPARAPOLQ
SCHEMBL3320048 0.84 DPP4 (0.55) DPP4DPP7PPARGPPARADPP8
SCHEMBL29633831 0.83 PPARG (0.49) DPP4DPP7PPARGPPARAPOLQ
SCHEMBL503201 0.81 PPARG (0.53) DPP4DPP7PPARGPPARAPOLQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
CN-118879592-A Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-11-01 CN disclosed
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 CN disclosed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
WO-2024083220-A1 LIGAND-OLIGONUCLEOTIDE CONJUGATE AND LINKER FOR CONJUGATE 上海京新生物医药有限公司 2024-04-25 WO disclosed
EP-4355755-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS Venatorx Pharmaceuticals, Inc. (US) 2024-04-24 EP disclosed
CN-111182880-B WNT compositions and process from serum-free culture conditions 安卡萨再生疗法公司 2024-01-09 CN disclosed
EP-4228707-A1 NANOMATERIAL AND METHODS OF USE THEREOF University of Connecticut (US) 2023-08-23 EP disclosed
CN-116457034-A Nanomaterial and method of use thereof 康涅狄格大学 2023-07-18 CN disclosed
CN-116445398-A WNT composition and purification method 小利兰斯坦福大学托管委员会 2023-07-18 CN disclosed
CN-114853866-A Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-08-05 CN disclosed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN disclosed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
WO-2022081721-A1 NANOMATERIAL AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2022-04-21 WO disclosed
EP-3976635-A1 METHODS OF TREATING HYPERLIPIDEMIA CONDITIONS WITH NETRIN-1 COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-06 EP disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
CN-114206911-A Methods of treating hyperlipidemia disorders with axon-targeting factor-1 compounds 加利福尼亚大学董事会 2022-03-18 CN disclosed
CN-114207129-A Agents and methods for replication, transcription and translation in semi-synthetic organisms 斯克利普斯研究所 2022-03-18 CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 CN disclosed