SCHEMBL503201

SCHEMBL503201

N[C@H](Cc1ccccc1C(F)(F)F)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.53
PPARA Q07869 1/20 0.53
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
NOS3 P29474 3/20 0.53
NOS1 P29475 3/20 0.53
NOS2 P35228 3/20 0.53
DPP4 P27487 3/20 0.51
FAP Q12884 2/20 0.51
DPP8 Q6V1X1 2/20 0.51
DPP9 Q86TI2 2/20 0.51
POLQ O75417 1/20 0.50
DPP7 Q9UHL4 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
MPO P05164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42976 1.00 PPARG (0.53) PPARGPPARAALPIPKMPTGS1
SCHEMBL42975 1.00 PPARG (0.53) PPARGPPARAALPIPKMPTGS1
SCHEMBL29410813 1.00 PPARG (0.53) PPARGPPARAALPIPKMPTGS1
SCHEMBL19143671 0.87 NOS3 (0.50) PPARGPPARAALPIPKMPTGS1
SCHEMBL14489706 0.87 NOS3 (0.52) PPARGPPARAALPIPKMPTGS1
SCHEMBL20038753 0.87 NOS3 (0.52) PPARGPPARAALPIPKMPTGS1
SCHEMBL5328323 0.86 NOS3 (0.46) PPARGPPARAALPIPKMPTGS1
SCHEMBL16938502 0.85 DPP4 (0.50) PPARGPPARADPP4FAPDPP8
SCHEMBL9492298 0.84 PPARG (0.57) PPARGPPARADPP4POLQDPP7
SCHEMBL26966057 0.84 POLQ (0.48) PPARGPPARAALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464324-B1 ANGIOTENSIN-1-RECEPTOR ANTAGONISTS FERRING BV (NL) 2021-04-07 EP claimed
US-20200102348-A1 ANGIOTENSIN-1-RECEPTOR ANTAGONISTS FERRING B.V. (NL) 2020-04-02 US claimed
US-10344054-B2 Angiotensin-1-receptor antagonists FERRING B.V. (NL) 2019-07-09 US claimed
EP-3464324-A1 ANGIOTENSIN-1-RECEPTOR ANTAGONISTS Ferring B.V. (NL) 2019-04-10 EP claimed
US-20170349629-A1 Angiotensin-1-Receptor Antagonists FERRING B.V. (NL) 2017-12-07 US claimed
WO-2017207760-A1 ANGIOTENSIN-1-RECEPTOR ANTAGONISTS FERRING B.V. (NL) 2017-12-07 WO claimed
EP-2036918-A1 PEPTIDE DERIVATIVE Vexon, Inc. (JP) 2009-03-18 EP claimed
US-20080009448-A1 Peptide Derivative VEXON, INC. (50%) (JP) 2008-01-10 US claimed
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY TRANSFERT PLUS LP (CA) 2026-03-26 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
US-20250302971-A1 Therapeutic Nanomaterials UNIV CONNECTICUT (US) 2025-10-02 US disclosed
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-02 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
US-7232803-B2 Antimicrobial compounds and formulations LYTIX BIOPHARMA AS (NO) 2007-06-19 US disclosed
US-20060194700-A1 Corrosion inhibitor systems for low, moderate and high temperature fluids and methods for making and using same WEATHERFORD/LAMB 2006-08-31 US disclosed
US-20060116296-A1 Shale Inhibition additive for oil/gas down hole fluids and methods for making and using same CLEARWATER INTERNATIONAL, L.L.C. 2006-06-01 US disclosed
US-6890902-B2 Cytotoxic modified lactoferrin peptides ALPHARMA AS (NO) 2005-05-10 US disclosed
US-20030195144-A1 Antimicrobial compounds and formulations LYTIX BIOPHARMA AS (NO) 2003-10-16 US disclosed
US-20030022821-A1 Bioactive peptides ALPHARMA AS 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302971-A1 Therapeutic Nanomaterials TIE1, TEKT1, POLRMT PPARG 3246/4885PPARA 2209/4885ALPI 4083/4885
US-20170349629-A1 Angiotensin-1-Receptor Antagonists AGTR1, AGTR2, REN PPARG 977/4885PPARA 1134/4885ALPI 3555/4885
US-20200102348-A1 ANGIOTENSIN-1-RECEPTOR ANTAGONISTS AGTR1, AGTR2, REN PPARG 977/4885PPARA 1134/4885ALPI 3555/4885
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 PPARG 4812/4885PPARA 4523/4885ALPI 563/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH PPARG 4002/4885PPARA 4497/4885ALPI 4559/4885
US-10344054-B2 Angiotensin-1-receptor antagonists AGTR1, AGTR2, AGT PPARG 1035/4885PPARA 1097/4885ALPI 3362/4885
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF JAK2, JAK1, CHMP4B PPARG 4634/4885PPARA 4154/4885ALPI 818/4885
US-20030195144-A1 Antimicrobial compounds and formulations LPO, CLPTM1, VIP PPARG 1529/4885PPARA 638/4885ALPI 1907/4885
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY VSIG8, MICA, CD74 PPARG 4616/4885PPARA 4835/4885ALPI 2844/4885
US-20030022821-A1 Bioactive peptides VIP, LITAF, LNPEP PPARG 2764/4885PPARA 1562/4885ALPI 712/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 PPARG 3003/4885PPARA 3778/4885ALPI 4755/4885
US-20080009448-A1 Peptide Derivative ARGLU1, NGLY1, NPR3 PPARG 4811/4885PPARA 4517/4885ALPI 4171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.