SCHEMBL29478367

SCHEMBL29478367

NC(=O)CC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.55
▸ ALOX15 P16050 1/20 0.55
▸ BLM P54132 1/20 0.55
▸ PMP22 Q01453 1/20 0.55
▸ DPP4 P27487 2/20 0.53
▸ DPP8 Q6V1X1 2/20 0.53
▸ DPP9 Q86TI2 2/20 0.53
▸ NOD1 Q9Y239 4/20 0.45
▸ CA2 P00918 5/20 0.43
▸ CA1 P00915 4/20 0.43
▸ FOLH1 Q04609 2/20 0.43
▸ RIMKLA Q8IXN7 1/20 0.43
▸ NAALAD2 Q9Y3Q0 1/20 0.43
▸ BMP1 P13497 1/20 0.43
▸ BACE1 P56817 1/20 0.39
▸ MMP2 P08253 1/20 0.38
▸ MMP9 P14780 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31015849 1.00 KMT2A (0.55) KMT2AALOX15BLMPMP22DPP4
SCHEMBL31378337 1.00 KMT2A (0.55) KMT2AALOX15BLMPMP22DPP4
SCHEMBL29630337 1.00 KMT2A (0.55) KMT2AALOX15BLMPMP22DPP4
SCHEMBL5970495 0.96 KMT2A (0.59) KMT2AALOX15BLMPMP22DPP4
SCHEMBL31378335 0.96 KMT2A (0.59) KMT2AALOX15BLMPMP22DPP4
SCHEMBL19375 0.96 KMT2A (0.59) KMT2AALOX15BLMPMP22DPP4
SCHEMBL30288867 0.95 FOLH1 (0.51) KMT2AALOX15BLMPMP22DPP4
SCHEMBL29706692 0.95 FOLH1 (0.51) KMT2AALOX15BLMPMP22DPP4
SCHEMBL29636521 0.95 FOLH1 (0.51) KMT2AALOX15BLMPMP22DPP4
SCHEMBL30596280 0.95 FOLH1 (0.51) KMT2AALOX15BLMPMP22DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 — — US disclosed
US-20250345411-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 — — US disclosed
US-12390520-B2 Vaccination in newborns and infants Cure Vac SE (DE) 2025-08-19 — — US disclosed
US-12391733-B2 Stapled intracellular-targeting antimicrobial peptides to treat infection DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-08-19 — — US disclosed
WO-2025065355-A1 POLYPEPTIDE PROBE AND KIT FOR EARLY DIAGNOSIS OF HUNTINGTON'S DISEASE 京东方科技集团股份有限公司 2025-04-03 — — WO disclosed
US-20240390478-A1 VACCINATION IN ELDERLY PATIENTS CureVac SE (DE) 2024-11-28 — — US disclosed
US-20240343765-A1 STAPLED INTRACELLULAR-TARGETING ANTIMICROBIAL PEPTIDES TO TREAT INFECTION DANA-FARBER CANCER INSTITUTE, INC. 2024-10-17 — — US disclosed
US-12036277-B2 Vaccination with mRNA-coded antigens CureVac SE (DE) 2024-07-16 — — US disclosed
US-20240197857-A1 VACCINATION WITH mRNA-CODED ANTIGENS CureVac SE (DE) 2024-06-20 — — US disclosed
US-11975064-B2 Vaccination with mRNA-coded antigens CureVac SE (DE) 2024-05-07 — — US disclosed
US-20230106577-A1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF AILERON THERAPEUTICS, INC. 2023-04-06 — — US disclosed
EP-3317294-B1 STABILIZED ANTI-MICROBIAL PEPTIDES DANA FARBER CANCER INST INC (US) 2023-03-15 — — EP disclosed
EP-3344275-B1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF AILERON THERAPEUTICS INC (US) 2023-03-08 — — EP disclosed
US-20230037284-A9 COMBINATION THERAPY OF PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2023-02-02 — — US disclosed
US-11478552-B2 Hybrid carriers for nucleic acid cargo CUREVAC AG (DE) 2022-10-25 — — US disclosed
WO-2022170108-A1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF IN PREVENTION OF RADIATION INJURY AILERON THERAPEUTICS, INC. (US) 2022-08-11 — — WO disclosed
CN-114853866-A Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-08-05 — — CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 — — CN disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 — — CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11478552-B2 Hybrid carriers for nucleic acid cargo HNRNPH1, HNRNPH3, SNRPE KMT2A 3349/4885ALOX15 2734/4885BLM 967/4885
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS HLA-DRB1, TLR3, TLR9 KMT2A 1880/4885ALOX15 3236/4885BLM 1885/4885
US-20240343765-A1 STAPLED INTRACELLULAR-TARGETING ANTIMICROBIAL PEPTIDES TO TREAT INFECTION VIP, SPPL2B, HM13 KMT2A 4793/4885ALOX15 3355/4885BLM 3040/4885
US-20230037284-A9 COMBINATION THERAPY OF PEPTIDOMIMETIC MACROCYCLES BID, FLT3, GRPR KMT2A 3413/4885ALOX15 4124/4885BLM 362/4885
US-20230106577-A1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF TP53, TP53BP1, MDM2 KMT2A 3448/4885ALOX15 4685/4885BLM 440/4885
US-12391733-B2 Stapled intracellular-targeting antimicrobial peptides to treat infection VIP, SPPL2B, HM13 KMT2A 4793/4885ALOX15 3355/4885BLM 3040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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