SCHEMBL29478403

SCHEMBL29478403

Cc1cccc(C[C@H](N)CC(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.48
ENPEP Q07075 1/20 0.48
CTBP2 P56545 1/20 0.45
FFAR1 O14842 1/20 0.45
POLB P06746 1/20 0.45
FOLH1 Q04609 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
TACR1 P25103 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CTSB P07858 2/20 0.42
MME P08473 1/20 0.42
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
IDO1 P14902 1/20 0.42
CTSL P07711 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29478376 1.00 ANPEP (0.48) ANPEPENPEPCTBP2FFAR1POLB
SCHEMBL2033289 1.00 ANPEP (0.48) ANPEPENPEPCTBP2FFAR1POLB
SCHEMBL2028584 1.00 ANPEP (0.48) ANPEPENPEPCTBP2FFAR1POLB
SCHEMBL2028585 1.00 ANPEP (0.48) ANPEPENPEPCTBP2FFAR1POLB
SCHEMBL5323971 0.84 S1PR2 (0.54) ANPEPCTBP2FFAR1TAAR1KDM4E
SCHEMBL5324141 0.84 ANPEP (0.46) ANPEPENPEPCTBP2FFAR1POLB
SCHEMBL15093267 0.82 CTBP2 (0.46) CTBP2FFAR1POLBFOLH1KDM4E
SCHEMBL289224 0.82 ANPEP (0.49) ANPEPENPEPFOLH1MMESLC7A5
SCHEMBL22734422 0.82 GRIA2 (0.55) ANPEPENPEPCTBP2FOLH1TAAR1
SCHEMBL30810322 0.82 GRIA2 (0.55) ANPEPENPEPCTBP2FOLH1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
CN-118879592-A Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-11-01 CN disclosed
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 CN disclosed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
CN-111182880-B WNT compositions and process from serum-free culture conditions 安卡萨再生疗法公司 2024-01-09 CN disclosed
CN-116445398-A WNT composition and purification method 小利兰斯坦福大学托管委员会 2023-07-18 CN disclosed
CN-116457034-A Nanomaterial and method of use thereof 康涅狄格大学 2023-07-18 CN disclosed
EP-4041249-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES The Scripps Research Institute (US) 2022-08-17 EP disclosed
WO-2022170108-A1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF IN PREVENTION OF RADIATION INJURY AILERON THERAPEUTICS, INC. (US) 2022-08-11 WO disclosed
CN-114853866-A Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-08-05 CN disclosed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN disclosed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
EP-3983543-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS The Scripps Research Institute (US) 2022-04-20 EP disclosed
EP-3976635-A1 METHODS OF TREATING HYPERLIPIDEMIA CONDITIONS WITH NETRIN-1 COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-06 EP disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
CN-114206911-A Methods of treating hyperlipidemia disorders with axon-targeting factor-1 compounds 加利福尼亚大学董事会 2022-03-18 CN disclosed
CN-114207129-A Agents and methods for replication, transcription and translation in semi-synthetic organisms 斯克利普斯研究所 2022-03-18 CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 CN disclosed