SCHEMBL5323971

SCHEMBL5323971

Cc1cccc(CCC(N)CC(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.54
S1PR1 P21453 1/20 0.54
TAAR1 Q96RJ0 2/20 0.49
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
FFAR1 O14842 1/20 0.43
CTBP2 P56545 1/20 0.43
GRM2 Q14416 1/20 0.43
GRM3 Q14832 1/20 0.43
NR3C2 P08235 1/20 0.43
SLC1A5 Q15758 1/20 0.42
LNPEP Q9UIQ6 1/20 0.42
DPP4 P27487 1/20 0.41
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
KIF11 P52732 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5324793 0.91 S1PR2 (0.51) S1PR2S1PR1TAAR1MEN1KMT2A
SCHEMBL5321285 0.87 S1PR2 (0.55) S1PR2S1PR1TAAR1MEN1MAPT
SCHEMBL2033289 0.84 ANPEP (0.48) TAAR1FFAR1CTBP2KDM4EALDH1A1
SCHEMBL2028585 0.84 ANPEP (0.48) TAAR1FFAR1CTBP2KDM4EALDH1A1
SCHEMBL29478376 0.84 ANPEP (0.48) TAAR1FFAR1CTBP2KDM4EALDH1A1
SCHEMBL29478403 0.84 ANPEP (0.48) TAAR1FFAR1CTBP2KDM4EALDH1A1
SCHEMBL2028584 0.84 ANPEP (0.48) TAAR1FFAR1CTBP2KDM4EALDH1A1
SCHEMBL3958700 0.83 S1PR2 (0.43) S1PR2S1PR1TAAR1MEN1MAPT
SCHEMBL3962878 0.83 S1PR2 (0.43) S1PR2S1PR1TAAR1MEN1MAPT
SCHEMBL3966151 0.83 S1PR2 (0.43) S1PR2S1PR1TAAR1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070258899-A1 Diagnostic and therapeutic agents KARYON-CTT LTD (FI) 2007-11-08 US disclosed
WO-2007113385-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070258899-A1 Diagnostic and therapeutic agents YBX1, MLX, TPX2 S1PR2 1899/4885S1PR1 1718/4885TAAR1 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.