SCHEMBL29478409

SCHEMBL29478409

N[C@H](CC(=O)O)Cc1cccnc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.57
NAPRT Q6XQN6 1/20 0.57
FDPS P14324 1/20 0.51
TBXAS1 P24557 11/20 0.50
KDM4E B2RXH2 1/20 0.50
RECQL P46063 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
ANPEP P15144 1/20 0.47
ERAP2 Q6P179 1/20 0.47
ERAP1 Q9NZ08 1/20 0.47
LMNA P02545 2/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2028393 1.00 DPP4 (0.57) DPP4NAPRTFDPSTBXAS1KDM4E
SCHEMBL2028392 1.00 DPP4 (0.57) DPP4NAPRTFDPSTBXAS1KDM4E
SCHEMBL2034613 1.00 DPP4 (0.57) DPP4NAPRTFDPSTBXAS1KDM4E
SCHEMBL29478423 1.00 DPP4 (0.57) DPP4NAPRTFDPSTBXAS1KDM4E
SCHEMBL27152857 0.88 DPP4 (0.51) DPP4NAPRTFDPSTBXAS1KDM4E
SCHEMBL27152858 0.88 DPP4 (0.51) DPP4NAPRTFDPSTBXAS1KDM4E
SCHEMBL27484444 0.84 TBXAS1 (0.55) NAPRTTBXAS1KDM4ERECQLCYP1A2
Hydrochloric Acid SCHEMBL27485858 0.83 TBXAS1 (0.56) NAPRTTBXAS1KDM4ERECQLCYP1A2
Hydrochloric Acid SCHEMBL27552750 0.83 TBXAS1 (0.56) NAPRTTBXAS1KDM4ERECQLCYP1A2
SCHEMBL27581965 0.82 NAPRT (0.59) NAPRTFDPSTBXAS1KDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
CN-118879592-A Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-11-01 CN disclosed
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 CN disclosed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
EP-4355755-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS Venatorx Pharmaceuticals, Inc. (US) 2024-04-24 EP disclosed
CN-111182880-B WNT compositions and process from serum-free culture conditions 安卡萨再生疗法公司 2024-01-09 CN disclosed
EP-4228707-A1 NANOMATERIAL AND METHODS OF USE THEREOF University of Connecticut (US) 2023-08-23 EP disclosed
CN-116445398-A WNT composition and purification method 小利兰斯坦福大学托管委员会 2023-07-18 CN disclosed
CN-116457034-A Nanomaterial and method of use thereof 康涅狄格大学 2023-07-18 CN disclosed
WO-2022265964-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS VenatoRx Pharmaceuticals, Inc. (US) 2022-12-22 WO disclosed
EP-4041247-A1 EUKARYOTIC SEMI-SYNTHETIC ORGANISMS The Scripps Research Institute (US) 2022-08-17 EP disclosed
CN-114853866-A Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-08-05 CN disclosed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN disclosed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
WO-2022081721-A1 NANOMATERIAL AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2022-04-21 WO disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
CN-114206911-A Methods of treating hyperlipidemia disorders with axon-targeting factor-1 compounds 加利福尼亚大学董事会 2022-03-18 CN disclosed
CN-114207129-A Agents and methods for replication, transcription and translation in semi-synthetic organisms 斯克利普斯研究所 2022-03-18 CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 CN disclosed