Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 11/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.44 |
| ▸ | CDK2 | P24941 | 10/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165317 | 1.00 | PDPK1 (0.51) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL11222102 | 0.85 | PDPK1 (0.63) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL4364340 | 0.85 | PDPK1 (0.49) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL29514836 | 0.83 | PDPK1 (0.56) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL215054 | 0.83 | PDPK1 (0.56) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL9809157 | 0.82 | PDPK1 (0.45) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL9204966 | 0.81 | PDPK1 (0.47) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL6379588 | 0.81 | PDPK1 (0.58) | PDPK1GDACDK1CCNB1CCNA2 | |
| Hydrochloric Acid SCHEMBL10339773 | 0.80 | PDPK1 (0.46) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL1074970 | 0.80 | POLA1 (0.57) | PDPK1GDACDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729355-A | PPM1A inhibitors and methods of using the same | 奎里斯公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114414790-A | Device and method for detecting liquid phase change | 北京碧澄生物科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108627636-B | Device and method for detecting liquid solidification | 北京碧澄生物科技有限公司 | 2022-03-01 | — | — | CN | disclosed |