SCHEMBL29514836

SCHEMBL29514836

CCCc1nc(N)c2[nH]cnc2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.56
GDA Q9Y2T3 1/20 0.56
POLA1 P09884 1/20 0.50
CDK1 P06493 9/20 0.48
CCNB1 P14635 9/20 0.48
CDK2 P24941 9/20 0.48
CCNA2 P20248 8/20 0.48
CCNA1 P78396 8/20 0.48
PIN1 Q13526 1/20 0.47
PI4KA P42356 2/20 0.44
PI4K2B Q8TCG2 2/20 0.44
PI4K2A Q9BTU6 2/20 0.44
PI4KB Q9UBF8 2/20 0.44
LMNA P02545 1/20 0.44
DRD3 P35462 1/20 0.44
XDH P47989 1/20 0.44
LRRK2 Q5S007 1/20 0.44
MAP3K5 Q99683 1/20 0.41
DPP4 P27487 1/20 0.41
PNP P00491 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215054 1.00 PDPK1 (0.56) PDPK1GDAPOLA1CDK1CCNB1
SCHEMBL1074970 0.90 POLA1 (0.57) PDPK1GDAPOLA1CDK1CCNB1
SCHEMBL11222102 0.90 PDPK1 (0.63) PDPK1GDAPOLA1CDK1CCNB1
SCHEMBL28299226 0.89 POLA1 (0.53) PDPK1GDAPOLA1CDK1CCNB1
Fumaric Acid SCHEMBL28313166 0.88 PDPK1 (0.44) PDPK1GDAPOLA1CDK1CCNB1
SCHEMBL30610405 0.88 CDK1 (0.53) PDPK1GDAPOLA1CDK1CCNB1
SCHEMBL1924592 0.86 PDPK1 (0.59) PDPK1GDAPOLA1CDK1CCNB1
SCHEMBL29592683 0.86 PDPK1 (0.59) PDPK1GDAPOLA1CDK1CCNB1
Hydrochloric Acid SCHEMBL26629016 0.85 CDK1 (0.51) PDPK1GDAPOLA1CDK1CCNB1
Water SCHEMBL28083708 0.85 PDPK1 (0.58) PDPK1GDAPOLA1CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746920-A1 HEMATOPOIETIC CELL TARGETING CONJUGATES AND RELATED METHODS Marrow Therapeutics, Inc. (US) 2026-05-27 EP disclosed
CN-122095092-A Inhibitor for inhibiting inhibin Beta E gene expression and application thereof 2026-05-26 CN disclosed
CN-122095091-A DsRNA for inhibiting LPA gene expression and application thereof 2026-05-26 CN disclosed
WO-2026101887-A1 NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME ILLUMINA, INC. (US) 2026-05-15 WO disclosed
CN-122038302-A Modified T cells and methods of making and using the same 哈佛学院校长同事会 2026-05-15 CN disclosed
WO-2026089806-A2 SAA1-TARGETED OLIGOMERIC COMPOUNDS, COMPOSITIONS AND USES N-LOREM FOUNDATION (US) 2026-04-30 WO disclosed
EP-4727955-A1 CYSTEINE-SUBSTITUTED RSV-F PROTEINS GlaxoSmithKline Biologicals S.A. (BE) 2026-04-22 EP disclosed
WO-2026044046-A1 PATTERNED MODIFIED OLIGONUCLEOTIDES FOR EXTENDED DURATION OF ACTION IONIS PHARMACEUTICALS, INC. (US) 2026-02-26 WO disclosed
WO-2026043966-A1 COMPOUNDS AND METHODS FOR MODULATING ALPHA-SYNUCLEIN EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2026-02-26 WO disclosed
EP-4680275-A1 RSV-F-ENCODING NUCLEIC ACIDS GlaxoSmithKline Biologicals S.A. (BE) 2026-01-21 EP disclosed
CN-109485676-B Novel nucleoside reverse transcriptase inhibitors for antiviral use 深圳市塔吉瑞生物医药有限公司 2022-07-15 CN disclosed
CN-105518146-B Therapeutic uses of genome editing with CRISPR/Cas systems 哈佛学院校长同事会 2022-07-15 CN disclosed
WO-2022150372-A1 GUIDE RNA DESIGNS AND COMPLEXES FOR TYPE V CAS SYSTEMS HORIZON DISCOVERY LTD. (GB) 2022-07-14 WO disclosed
WO-2022150367-A1 GUIDE RNA DESIGNS AND COMPLEXES FOR TRACR-LESS TYPE V CAS SYSTEMS HORIZON DISCOVERY LTD. (GB) 2022-07-14 WO disclosed
WO-2022150369-A1 COMPOUNDS FOR THE TREATMENT OF BATTEN DISEASE EXICURE OPERATING COMPANY (US) 2022-07-14 WO disclosed
WO-2022122689-A1 RNA MANUFACTURING BioNTech SE (DE) 2022-06-16 WO disclosed
WO-2022115539-A2 MODULATING TRANSCRIPTIONAL CONDENSATES WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2022-06-02 WO disclosed
WO-2022094615-A1 COMPOUNDS AND METHODS FOR INCREASED ANTISENSE ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-05 WO disclosed
CN-114404581-A Cancer vaccine 摩登纳特斯有限公司 2022-04-29 CN disclosed
EP-3976788-A1 OLIGONUCLEOTIDE THERAPY FOR WOLMAN DISEASE AND CHOLESTERYL ESTER STORAGE DISEASE Deep Genomics Incorporated (CA) 2022-04-06 EP disclosed