Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20748279 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29157420 | 0.98 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL657027 | 0.97 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11794645 | 0.95 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL11726853 | 0.93 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL3043144 | 0.92 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL7106841 | 0.90 | KDM4E (0.61) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL7041242 | 0.87 | MAPT (0.68) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL6887590 | 0.87 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL19935557 | 0.85 | MEN1 (0.48) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106750303-B | A kind of polyarylether of the group containing methyl piperidine and preparation method thereof | 吉林大学 | 2019-03-19 | — | — | CN | claimed |
| CN-108997242-A | Substituted phenyl pyrazole quinoline ketone derivatives and preparation and application | 浙江大学 | 2018-12-14 | — | — | CN | claimed |
| CN-106750303-A | A kind of polyarylether containing methyl piperidine group and preparation method thereof | 吉林大学 | 2017-05-31 | — | — | CN | claimed |
| US-9598361-B1 | Amino substituted acetamide derivative | KING SAUD UNIVERSITY (SA) | 2017-03-21 | — | — | US | claimed |
| EP-1727782-B1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 2012-08-22 | — | — | EP | claimed |
| US-7750156-B2 | Method of producing aminophenol compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | claimed |
| CN-100478325-C | Preparation method for aminophenol compound | OTSUKA PHARMA CO LTD (JP) | 2009-04-15 | — | — | CN | claimed |
| US-20070219374-A1 | Method of Producing Aminophenol Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | claimed |
| CN-1938261-A | Preparation method for aminophenol compound | OTSUKA PHARMA CO LTD (JP) | 2007-03-28 | — | — | CN | claimed |
| EP-1727782-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-12-06 | — | — | EP | claimed |
| WO-2005092832-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | WO | claimed |
| EP-0171037-B1 | 3-CARBONYL-1-AMINOALKYL-1H-INDOLES USEFUL AS ANALGESICS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-06-17 | — | — | EP | claimed |
| US-5013732-A | Analgesics | STERLING DRUG INC. (US) | 1991-05-07 | — | — | US | claimed |
| US-4978664-A | Analgesic, anti-rheumatic, and anti-inflammatory agent | STERLING DRUG INC. (US) | 1990-12-18 | — | — | US | claimed |
| US-4885295-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | STERLING DRUG INC. (US) | 1989-12-05 | — | — | US | claimed |
| US-RE32761-E | ANALGESICS, ANTIRHEUMATIC AND ANTIINFLAMMATORY AGENT | STERLING DRUG INC. (US) | 1988-10-04 | — | — | US | claimed |
| US-4634776-A | ANALGESIC, ANTIRHEUMATIC, ANTIINFLAMMATORY | STERLING DRUG, INC. (US) | 1987-01-06 | — | — | US | claimed |
| US-4581354-A | ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1986-04-08 | — | — | US | claimed |
| CN-117820191-B | Diphenylamine compound and preparation method, application and pharmaceutical composition thereof | FUDAN UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-3935227-A | ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219374-A1 | Method of Producing Aminophenol Compounds | PAH, CYP1A1, CYP1B1 | ALDH1A1 199/4885MAPT 4188/4885KDM4E 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.