SCHEMBL29479481

SCHEMBL29479481

COC(Cl)C(Cl)OC.[Ni]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24250830 0.95
SCHEMBL15277279 0.75
SCHEMBL383738 0.75
SCHEMBL15277316 0.75
SCHEMBL8506053 0.72
SCHEMBL15277289 0.72
SCHEMBL9293579 0.72
SCHEMBL62080 0.70
SCHEMBL19649 0.70
SCHEMBL8927970 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731703-A1 LINEAR POLYAMINES HAVING A LONG CARBON CHAIN, METHOD FOR PRODUCING SAME, AND USES THEREOF Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2026-04-29 EP claimed
WO-2024261162-A1 LINEAR POLYAMINES HAVING A LONG CARBON CHAIN, METHOD FOR PRODUCING SAME, AND USES THEREOF Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2024-12-26 WO claimed
EP-4731703-A1 LINEAR POLYAMINES HAVING A LONG CARBON CHAIN, METHOD FOR PRODUCING SAME, AND USES THEREOF Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2026-04-29 EP disclosed
CN-119866338-A Tyrosine kinase 2 inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-22 CN disclosed
CN-119301113-A Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors 豪夫迈·罗氏有限公司 2025-01-10 CN disclosed
WO-2024261162-A1 LINEAR POLYAMINES HAVING A LONG CARBON CHAIN, METHOD FOR PRODUCING SAME, AND USES THEREOF Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2024-12-26 WO disclosed
CN-112566906-B Substituted quinazolinone derivatives and their use as positive allosteric modulators of MGLUR4 多曼治疗学公司 2024-11-12 CN disclosed
CN-118251389-A Pyridyl derivatives as sodium channel activators 泽农医药公司 2024-06-25 CN disclosed
CN-118043308-A Bond formation method based on coupling reaction 中外制药株式会社 2024-05-14 CN disclosed
CN-117794898-A 3-pyrrolylsulfonamide compounds as GPR17 antagonists 瑞文德医疗公众有限公司 2024-03-29 CN disclosed
CN-113039182-B Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment 伊文蒂瓦公司 2024-02-20 CN disclosed
CN-117561058-A CDK2 inhibitors and methods of use thereof 塞迪拉治疗股份有限公司 2024-02-13 CN disclosed
CN-111936503-B Oxazine monoacylglycerol lipase (MAGL) inhibitors 豪夫迈·罗氏有限公司 2023-09-12 CN disclosed
CN-116547287-A Inhibitors of APOL1 and methods of use thereof 弗特克斯药品有限公司 2023-08-04 CN disclosed
CN-116507608-A Compounds, compositions, and methods 戴纳立制药公司 2023-07-28 CN disclosed
CN-116096723-A Heterocyclic compounds useful as MAGL inhibitors 豪夫迈·罗氏有限公司 2023-05-09 CN disclosed
CN-114401969-A Heterocyclic compounds 豪夫迈·罗氏有限公司 2022-04-26 CN disclosed
CN-114401968-A Novel heterocyclic monoacylglycerol lipase (MAGL) inhibitors 豪夫迈·罗氏有限公司 2022-04-26 CN disclosed
CN-114364684-A Heterocyclic compounds 豪夫迈·罗氏有限公司 2022-04-15 CN disclosed
CN-114269755-A 4,4A,5,7,8, 8A-hexapyrido [4,3-B ] [1,4] oxazin-3-one compounds as MAGL inhibitors 豪夫迈·罗氏有限公司 2022-04-01 CN disclosed