Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cilobamine SCHEMBL1816553 | 1.00 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Cilobamine SCHEMBL6707709 | 1.00 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Cilobamine SCHEMBL122050 | 0.94 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Cilobamine SCHEMBL29365831 | 0.94 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL11883766 | 0.65 | OPRL1 (0.41) | SLC6A4SLC6A3SLC6A2CYP1A2CYP3A4 | |
| SCHEMBL728809 | 0.62 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL5472565 | 0.62 | SLC6A3 (0.67) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL5472576 | 0.62 | SLC6A3 (0.67) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL17999757 | 0.61 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL17999754 | 0.61 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116963744-A | Pharmaceutical, therapeutic combination and method for preventing viral and microbial infections and their sequelae | 拓比利亚欧斯特有限公司(ACN 652 771 670) | 2023-10-27 | — | — | CN | claimed |
| CN-115120592-A | Composition for relieving skin pruritus and allergy, clinical test method and application | 傅绍义 | 2022-09-30 | — | — | CN | claimed |
| CN-114191553-A | Medicine for resisting novel coronavirus SARS-CoV-2 and its application | 中国医学科学院病原生物学研究所 | 2022-03-18 | — | — | CN | claimed |
| CN-117242080-A | Boron-containing pyrazole compounds, compositions comprising the same, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116963744-A | Pharmaceutical, therapeutic combination and method for preventing viral and microbial infections and their sequelae | 拓比利亚欧斯特有限公司(ACN 652 771 670) | 2023-10-27 | — | — | CN | disclosed |
| CN-116829555-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116332873-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115120592-A | Composition for relieving skin pruritus and allergy, clinical test method and application | 傅绍义 | 2022-09-30 | — | — | CN | disclosed |
| CN-115058501-A | Method for detecting drug effect of muscle-relaxing waist-strengthening drug by using gene sequencing | 广州医药研究总院有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-115003279-A | Prodrug compositions and methods of treatment | 阿奎斯蒂弗医疗股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114729000-A | Compounds for the treatment of CNS disorders | 萨奇治疗股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-112494491-B | Use of Spanish in preparing medicine for preventing or treating neurodegenerative disease | 东北大学 | 2022-04-01 | — | — | CN | disclosed |