Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28936297 | 1.00 | MAPT (0.48) | MAPTHPSEHDAC6TP53RAB9A | |
| SCHEMBL28695257 | 0.89 | MAPT (0.50) | MAPTHDAC6TP53RXFP1HDAC3 | |
| SCHEMBL29479729 | 0.89 | MAPT (0.50) | MAPTHDAC6TP53RXFP1HDAC3 | |
| SCHEMBL23033302 | 0.86 | CETP (0.48) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL29479718 | 0.84 | MAPT (0.44) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL23012156 | 0.84 | MAPT (0.44) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL23012158 | 0.84 | MAPT (0.44) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL29479831 | 0.83 | CETP (0.56) | HDAC6 | |
| SCHEMBL28706421 | 0.83 | CETP (0.56) | HDAC6 | |
| SCHEMBL23012864 | 0.81 | KDM4D (0.45) | MAPTHDAC6TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |