Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479718 | 1.00 | MAPT (0.44) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL23012158 | 1.00 | MAPT (0.44) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL29479632 | 0.84 | MAPT (0.48) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL28936297 | 0.84 | MAPT (0.48) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL28695257 | 0.84 | MAPT (0.50) | MAPTHDAC6TP53HDAC3HDAC1 | |
| SCHEMBL29479729 | 0.84 | MAPT (0.50) | MAPTHDAC6TP53HDAC3HDAC1 | |
| SCHEMBL23033302 | 0.79 | CETP (0.48) | MAPTHDAC6TP53RAB9ASMN1; SMN2 | |
| SCHEMBL28706421 | 0.77 | CETP (0.56) | HDAC6 | |
| SCHEMBL29479831 | 0.77 | CETP (0.56) | HDAC6 | |
| SCHEMBL23033343 | 0.75 | RAB9A (0.50) | MAPTTP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |