Sugi Predict

Sugi Predict / Compounds / SCHEMBL29479866

SCHEMBL29479866

SCHEMBL29479866

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(C)C)C(C)C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 7/20 0.51
▸ NPY4R P50391 7/20 0.51
▸ NPY5R Q15761 7/20 0.51
▸ NPY1R P25929 5/20 0.51
▸ KDM1A O60341 1/20 0.51
▸ MAOB P27338 1/20 0.51
▸ KDM5A P29375 1/20 0.51
▸ KDM1B Q8NB78 1/20 0.51
▸ TFPI P10646 4/20 0.51
▸ RAMP3 O60896 3/20 0.50
▸ CALCR P30988 3/20 0.50
▸ OPRD1 P41143 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30648444 0.98 NPY2R (0.51) NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL29479863 0.97 NPY2R (0.52) NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL29855903 0.93 NPY2R (0.53) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL38662669 0.92 OPRD1 (0.47) NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL30906558 0.91 RAMP3 (0.47) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30906409 0.91 RAMP3 (0.47) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL29881695 0.91 OPRD1 (0.53) OPRD1
SCHEMBL30431793 0.91 NPY2R (0.52) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30906340 0.91 NPY2R (0.57) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30930170 0.91 NPY2R (0.54) NPY2RNPY4RNPY5RNPY1RRAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213534-B Anti-human PlGF (platelet-derived growth factor) murine monoclonal antibody and application thereof 南京佰抗生物科技有限公司 2022-06-03 — — CN disclosed
CN-114213534-A Anti-human PlGF (platelet-derived growth factor) mouse-derived monoclonal antibody and application thereof 南京佰抗生物科技有限公司 2022-03-22 — — CN disclosed
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