Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 4/20 | 0.34 |
| ▸ | KDM4B | O94953 | 4/20 | 0.34 |
| ▸ | KDM5C | P41229 | 4/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 7/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22716885 | 0.83 | GCG (0.39) | EGLN1JAK2JAK3 | |
| SCHEMBL29567469 | 0.83 | GCG (0.39) | EGLN1JAK2JAK3 | |
| SCHEMBL22736178 | 0.83 | JAK2 (0.36) | EGLN1GRM4JAK2JAK1JAK3 | |
| SCHEMBL29480593 | 0.79 | GRM4 (0.40) | GRM4KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL22736157 | 0.72 | JAK3 (0.42) | GRM4JAK2JAK1JAK3TYK2 | |
| SCHEMBL22736159 | 0.71 | GRM4 (0.45) | GRM4JAK2JAK1JAK3TYK2 | |
| SCHEMBL29567533 | 0.71 | EGLN1 (0.36) | EGLN1GRM4JAK2JAK1JAK3 | |
| SCHEMBL22716872 | 0.70 | GRM4 (0.44) | GRM4 | |
| SCHEMBL22736014 | 0.70 | GRM4 (0.38) | GRM4JAK2JAK1JAK3TYK2 | |
| SCHEMBL29480627 | 0.70 | GRM4 (0.38) | GRM4JAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-B | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-114174294-B | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |