Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10153813 | 0.86 | PTGS1 (0.33) | — | |
| SCHEMBL3386734 | 0.81 | JAK2 (0.30) | JAK2JAK1TYK2CNR1CNR2 | |
| SCHEMBL14002903 | 0.79 | — | — | |
| SCHEMBL23692415 | 0.76 | — | — | |
| Dimethylamine SCHEMBL19811940 | 0.76 | APP (0.39) | CNR1CNR2 | |
| SCHEMBL14814813 | 0.73 | ALDH1A1 (0.35) | CNR1CNR2 | |
| SCHEMBL9995800 | 0.72 | CES1 (0.30) | JAK2JAK1TYK2 | |
| Dimethylamine SCHEMBL28178194 | 0.72 | MEN1 (0.31) | CNR1CNR2 | |
| SCHEMBL309951 | 0.72 | CES1 (0.33) | — | |
| SCHEMBL14814712 | 0.71 | CES1 (0.38) | JAK2JAK1TYK2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |