Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.37 |
| ▸ | GCG | P01275 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
| ▸ | BMP4 | P12644 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480747 | 0.81 | GRM4 (0.37) | EGLN1GRM4 | |
| SCHEMBL29480538 | 0.78 | ADORA2A (0.34) | EGLN1GRM4MAPT | |
| SCHEMBL22736011 | 0.78 | GRM4 (0.35) | EGLN1GRM4 | |
| SCHEMBL29480656 | 0.78 | GRM4 (0.35) | EGLN1GRM4 | |
| SCHEMBL22735928 | 0.75 | GRM4 (0.33) | EGLN1GRM4 | |
| SCHEMBL29480752 | 0.75 | GRM4 (0.33) | EGLN1GRM4 | |
| SCHEMBL29480647 | 0.75 | MELK (0.51) | MELKEGLN1GCGKDRFLT1 | |
| SCHEMBL12199747 | 0.70 | OGA (0.44) | MAPT | |
| SCHEMBL12181521 | 0.69 | CYP11B1 (0.43) | KDRMAPT | |
| SCHEMBL12181379 | 0.69 | CYP3A4 (0.36) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |