Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480995 | 1.00 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3290836 | 1.00 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3287272 | 0.93 | P2RX7 (0.87) | P2RX7 | |
| SCHEMBL3292654 | 0.93 | P2RX7 (0.86) | P2RX7 | |
| SCHEMBL3288037 | 0.91 | P2RX7 (0.83) | P2RX7 | |
| SCHEMBL3290343 | 0.91 | P2RX7 (0.83) | P2RX7 | |
| SCHEMBL3291486 | 0.90 | P2RX7 (0.81) | P2RX7 | |
| SCHEMBL3287548 | 0.88 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL3292896 | 0.88 | P2RX7 (0.78) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5312514 | 0.88 | P2RX7 (0.78) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103072-A | Methods of treating neurological disorders using anticholinergic agents | 帕克斯医学有限公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4366828-A1 | METHODS FOR TREATING NERVOUS SYSTEM DISORDERS WITH ANTIPURINERGIC AGENTS | Paxmedica, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| CN-116744914-A | Administration of anti-purinergic compositions for the treatment of neurological disorders | 帕克斯医学有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-4228642-A1 | ADMINISTRATION OF ANTIPURINERGIC COMPOSITIONS FOR TREATING NERVOUS SYSTEM DISORDERS | Paxmedica, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2023027994-A1 | METHODS FOR TREATING NERVOUS SYSTEM DISORDERS WITH ANTIPURINERGIC AGENTS | PAXMEDICA, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022087176-A1 | ADMINISTRATION OF ANTIPURINERGIC COMPOSITIONS FOR TREATING NERVOUS SYSTEM DISORDERS | PAXMEDICA, INC. (US) | 2022-04-28 | — | — | WO | disclosed |