Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | LPL | P06858 | 1/20 | 0.48 |
| ▸ | LIPC | P11150 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660239 | 0.89 | TAAR1 (0.68) | TAAR1MAOBMPOAOC3LMNA | |
| SCHEMBL8212198 | 0.86 | TAAR1 (0.60) | TAAR1HTR2AMAOAMAOBAOC3 | |
| SCHEMBL2302649 | 0.84 | KMT2A (0.50) | TAAR1HTR2AMAOBMPOLMNA | |
| SCHEMBL28963713 | 0.84 | HTR2A (0.58) | HTR2AMAOAMAOBSIGMAR1SMN1; SMN2 | |
| SCHEMBL29588181 | 0.84 | HTR2A (0.58) | HTR2AMAOAMAOBSIGMAR1SMN1; SMN2 | |
| SCHEMBL9587704 | 0.80 | HRH1 (0.53) | TAAR1LPLLIPCMAOBMPO | |
| SCHEMBL20382473 | 0.79 | HTR2A (0.52) | TAAR1HTR2ALPLMAOBAOC3 | |
| SCHEMBL8526001 | 0.78 | TAAR1 (0.75) | TAAR1MAOBMPOAOC3LMNA | |
| SCHEMBL54347 | 0.78 | HTR2A (0.70) | TAAR1HTR2AMAOAMAOBSIGMAR1 | |
| SCHEMBL13470658 | 0.77 | NPC1 (0.56) | HTR2AMAOASIGMAR1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194738-B | Preparation method of 1,2, 3-trisubstituted 4-quinolone derivative | 华侨大学 | 2022-04-05 | — | — | CN | disclosed |