SCHEMBL54347

SCHEMBL54347

c1ccc(CCCc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.70
SIGMAR1 Q99720 3/20 0.65
MAOA P21397 1/20 0.65
MAOB P27338 2/20 0.62
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61
ALOX15 P16050 1/20 0.61
ALOX12 P18054 1/20 0.61
CASP1 P29466 1/20 0.61
HSD17B10 Q99714 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
IDO1 P14902 1/20 0.59
HDAC3 O15379 1/20 0.59
MAPK1 P28482 1/20 0.59
ADRA1A P35348 1/20 0.59
HDAC4 P56524 1/20 0.59
SLC6A3 Q01959 1/20 0.59
HDAC1 Q13547 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC2 Q92769 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9069707 0.97 HTR2A (0.75) HTR2ASIGMAR1MAOAMAOBALDH1A1
SCHEMBL10354668 0.97 HTR2A (0.67) HTR2ASIGMAR1MAOAMAOBALDH1A1
Ammonia Solution, Strong SCHEMBL8817973 0.97 HTR2A (0.67) HTR2ASIGMAR1MAOAMAOBALDH1A1
SCHEMBL29268834 0.97 HTR2A (0.67) HTR2ASIGMAR1MAOAMAOBALDH1A1
SCHEMBL10831414 0.97 HTR2A (0.67) HTR2ASIGMAR1MAOAMAOBALDH1A1
SCHEMBL28353517 0.94 HTR2A (0.64) HTR2ASIGMAR1MAOAMAOBALDH1A1
SCHEMBL15347959 0.94 HTR2A (0.71) HTR2ASIGMAR1MAOAMAOBALDH1A1
SCHEMBL451456 0.93 MAOA (0.74) HTR2ASIGMAR1MAOAMAOBALDH1A1
SCHEMBL6546948 0.90 SIGMAR1 (0.71) SIGMAR1MAOAMAOB
SCHEMBL8095284 0.90 SIGMAR1 (0.71) SIGMAR1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3594 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4520775-B1 NITROGEN-CONTAINING HETEROCYCLIC POLYMER, AND POLYMER FILM AND USE THEREOF WUHAN LIMO TECH CO LTD (CN) 2026-05-06 EP claimed
EP-4049841-B1 HYBRID RESIN COMPOSITION CUBICURE GMBH (AT) 2026-03-18 EP claimed
CN-120058455-A Method for reducing tar amount in cumene preparation process 万华化学集团股份有限公司 2025-05-30 CN claimed
EP-4131553-B1 PRODUCTION METHOD FOR SOLID-STATE BATTERY, AND SOLID-STATE BATTERY TERAWATT TECH K K (JP) 2025-04-23 EP claimed
US-12252631-B2 Endoscopic coating composition, endoscopic lubricating member, method for producing endoscopic lubricating member, endoscopic flexible tube, and endoscope FUJIFILM CORPORATION (JP) 2025-03-18 US claimed
EP-4520775-A1 NITROGEN-CONTAINING HETEROCYCLIC POLYMER, AND POLYMER FILM AND USE THEREOF Wuhan Limo Technology Co., Ltd (CN) 2025-03-12 EP claimed
CN-119497730-A Process for producing polyarylene (ether) sulfones with improved properties 巴斯夫欧洲公司 2025-02-21 CN claimed
CN-119350170-A Diphenylpropane derivative and preparation method and application thereof 山东阳谷华泰化工股份有限公司 2025-01-24 CN claimed
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
EP-4466319-A1 HIGH PERFORMANCE THERMOSET RESINS FOR 3D PRINTING Noga 3D Innovations Ltd (IL) 2024-11-27 EP claimed
US-4139577-A USED IN CASTINGS AND REINFORCED LAMINATES ICI AMERICAS INC. (US) 1979-02-13 US claimed
US-4100344-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1978-07-11 US claimed
US-4093601-A Vinyl esters of tetracarboxylic acids and resins derived therefrom ICI AMERICAS INC. (US) 1978-06-06 US claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-4061631-A STABILIZER CIBA-GEIGY CORPORATION (US) 1977-12-06 US claimed
US-4058503-A FROM AN ANHYDRIDE AND A DIHYDRAZIDE BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-11-15 US claimed
US-4048148-A Polyazomethine fibers and films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-13 US claimed
US-4028354-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1977-06-07 US claimed
US-3996405-A ETHYLDIPHENYLMETHANE NCR CORPORATION (US) 1976-12-07 US claimed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US claimed