Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | PKM | P14618 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958872 | 1.00 | MAPT (0.62) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL1699958 | 0.93 | MAPT (0.72) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL30468003 | 0.93 | MAPT (0.72) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL19204113 | 0.89 | MAPT (0.62) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL1958532 | 0.88 | MAPT (0.65) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL1957750 | 0.87 | MAPT (0.63) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL30003577 | 0.87 | MAPT (0.55) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL22581507 | 0.87 | MAPT (0.52) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL30777658 | 0.87 | MAPT (0.52) | MAPTPKMPOLBKDM4EL3MBTL1 | |
| SCHEMBL21751695 | 0.86 | MAPT (0.59) | MAPTPKMPOLBL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084904-A | Benzamide compounds | 里科瑞尔姆IP控股有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-111801327-B | Benzamide compounds | 里科瑞尔姆IP控股有限责任公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114126616-A | Nanoparticle formulations of BCL-2 inhibitors | 里科瑞尔姆IP控股有限责任公司 | 2022-03-01 | — | — | CN | disclosed |