Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.57 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.50 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029434 | 1.00 | ITGAV (0.57) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029455 | 0.92 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029491 | 0.92 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029482 | 0.92 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029480 | 0.86 | ITGAV (0.51) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL29482180 | 0.82 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029475 | 0.82 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24363164 | 0.82 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL21706079 | 0.82 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL21705682 | 0.82 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481814-B1 | TETRAHYDRONAPHTHYRIDINEPENTANAMIDE INTEGRIN ANTAGONISTS | UNIV ROCKEFELLER (US) | 2022-04-27 | — | — | EP | disclosed |