SCHEMBL29482312

SCHEMBL29482312

CC1(C)O[C@H]2[C@@H](O1)[C@](C#N)(c1ccc3c(N)ncnn13)O[C@@H]2COP(=O)(O)Oc1ccccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ P2RX1 P51575 1/20 0.35
▸ P2RX3 P56373 1/20 0.35
▸ P2RX4 Q99571 1/20 0.35
▸ POLRMT O00411 1/20 0.34
▸ TMPRSS2 O15393 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24305088 1.00 P2RX1 (0.35) P2RX1P2RX3P2RX4POLRMTTMPRSS2
SCHEMBL29413313 0.97 P2RX1 (0.34) P2RX1P2RX3P2RX4POLRMTTMPRSS2
SCHEMBL29472403 0.93 TMPRSS2 (0.33) P2RX1P2RX3P2RX4POLRMTTMPRSS2
SCHEMBL24339518 0.93 TMPRSS2 (0.33) P2RX1P2RX3P2RX4POLRMTTMPRSS2
SCHEMBL24407340 0.89 P2RX1 (0.35) P2RX1P2RX3P2RX4POLRMT
SCHEMBL24917308 0.87 P2RX1 (0.38) P2RX1P2RX3P2RX4POLRMTTMPRSS2
SCHEMBL25915014 0.86 P2RX1 (0.37) P2RX1P2RX3P2RX4POLRMTTMPRSS2
SCHEMBL24304405 0.85 TMPRSS2 (0.30) TMPRSS2
SCHEMBL24304412 0.85 TMPRSS2 (0.30) TMPRSS2
SCHEMBL24340389 0.85 TMPRSS2 (0.30) TMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473314-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-11-18 — — US disclosed
EP-4537828-A2 PHOSPHOLIPID COMPOUNDS AND USES THEREOF Gilead Sciences, Inc. (US) 2025-04-16 — — EP disclosed
EP-4200301-B1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES INC (US) 2025-02-26 — — EP disclosed
US-12208110-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-01-28 — — US disclosed
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-11963967-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-04-23 — — US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 — — US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 — — US disclosed
US-20230248753-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-05-12 — — US disclosed
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-03-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RX1 1404/4885P2RX3 1365/4885P2RX4 1140/4885
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RX1 1502/4885P2RX3 1485/4885P2RX4 1240/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RX1 1502/4885P2RX3 1485/4885P2RX4 1240/4885
US-12208110-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS1, SGMS2 P2RX1 924/4885P2RX3 1158/4885P2RX4 911/4885
US-20230248753-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RX1 1404/4885P2RX3 1365/4885P2RX4 1140/4885
US-11963967-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RX1 1404/4885P2RX3 1365/4885P2RX4 1140/4885
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RX1 1502/4885P2RX3 1485/4885P2RX4 1240/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RX1 1502/4885P2RX3 1485/4885P2RX4 1240/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RX1 1502/4885P2RX3 1485/4885P2RX4 1240/4885
US-12473314-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RX1 1502/4885P2RX3 1485/4885P2RX4 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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