Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567427 | 0.88 | OPRM1 (0.56) | SLC6A2OPRM1OPRD1 | |
| SCHEMBL25286047 | 0.88 | CALCRL (0.42) | SLC6A2CALCRLREN | |
| SCHEMBL25286046 | 0.88 | CALCRL (0.42) | SLC6A2CALCRLREN | |
| SCHEMBL31548693 | 0.87 | CALCRL (0.59) | SLC6A2CALCRLRENAGTR1AGTR2 | |
| SCHEMBL11157497 | 0.87 | SLC6A2 (0.58) | SLC6A2RENOPRM1OPRD1 | |
| SCHEMBL11157501 | 0.87 | SLC6A2 (0.58) | SLC6A2RENOPRM1OPRD1 | |
| SCHEMBL29770378 | 0.85 | SLC6A2 (0.62) | SLC6A2CALCRLREN | |
| SCHEMBL13130786 | 0.85 | EPHA2 (0.59) | SLC6A2CALCRLOPRM1OPRD1 | |
| SCHEMBL29896174 | 0.85 | SLC6A2 (0.56) | SLC6A2OPRM1OPRD1F2 | |
| SCHEMBL31233755 | 0.85 | SLC6A2 (0.64) | SLC6A2CALCRLOPRM1OPRD1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240180997-A1 | PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASES | BHATNAGAR RAJENDRA SAHAI (US) | 2024-06-06 | — | — | US | disclosed |
| EP-4203988-A2 | PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASES | Bhatnagar, Rajendra, Sahai (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022047225-A2 | PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASES | BHATNAGAR RAJENDRA SAHAI (US) | 2022-03-03 | — | — | WO | disclosed |